3D sheath flow using hydrodynamic position control of the sample flow

Hironobu Sato*, Yutaka Sasamoto, Daisuke Yagyu, Tetsushi Sekiguchi, Shuichi Shoji

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


3D sheath flow was realized using hydrodynamic position control of the sample flow. The symmetric microgrooves formed on the channel walls were utilized to generate local directional streams. The sample introduced into the grooved area was shifted to the center region of the microchannel, and 3D sheath flow was formed passively. Using CFD (computational fluid dynamics) simulation, the flow shift area was designed to achieve 3D sheath flow no longer than 500 νm in channel length. Sample flow shift behavior was observed by using a confocal microscope. Since the structure of the inlets was very simple, it was possible to fabricate an in-plane multi-sample 3D sheath flow device. As a demonstration, a two-sample 3D sheath flow device was fabricated. The separated two-sample 3D sheath flow configuration was clearly observed.

Original languageEnglish
Pages (from-to)2211-2216
Number of pages6
JournalJournal of Micromechanics and Microengineering
Issue number11
Publication statusPublished - 2007 Nov 1

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Mechanics of Materials
  • Mechanical Engineering
  • Electrical and Electronic Engineering


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