TY - JOUR
T1 - Absence of diglyceride kinase activity in the photoreceptor cells of Drosophila mutants
AU - Yoshioka, Tohru
AU - Inoue, Hiroko
AU - Hotta, Yoshiki
PY - 1984/2/29
Y1 - 1984/2/29
N2 - Diglyceride kinase (DG) activity was found to be almost absent in the photoreceptor cells of Drosophila vision mutants, norpA (no receptor potential A). Other enzymes related to the phosphatidic acid (PA) metabolism, such as monoacyl-glycerophosphate acyltransferase and PA phosphatase, were normal in the mutant. The deficiency in PA content in the retinular cells of norpA, demonstrated by 32P incorporation in vivo is, therefore, due to abnormal reduction in DG kinase activity. The DG kinase was found to be localized in the retinular cell by assaying its activity in the mutants rdgA (receptor cells degenerated) and sine oculis (compound eyes absent).
AB - Diglyceride kinase (DG) activity was found to be almost absent in the photoreceptor cells of Drosophila vision mutants, norpA (no receptor potential A). Other enzymes related to the phosphatidic acid (PA) metabolism, such as monoacyl-glycerophosphate acyltransferase and PA phosphatase, were normal in the mutant. The deficiency in PA content in the retinular cells of norpA, demonstrated by 32P incorporation in vivo is, therefore, due to abnormal reduction in DG kinase activity. The DG kinase was found to be localized in the retinular cell by assaying its activity in the mutants rdgA (receptor cells degenerated) and sine oculis (compound eyes absent).
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U2 - 10.1016/0006-291X(84)91664-4
DO - 10.1016/0006-291X(84)91664-4
M3 - Article
C2 - 6322785
AN - SCOPUS:0021772721
SN - 0006-291X
VL - 119
SP - 389
EP - 395
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 1
ER -