Analysis of Facilitated Oxygen Transport in a Liquid Membrane of Hemoglobin

Xue Si Chen, Hiroyuki Nishide*, Eishun Tsuchida

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)


A liquid membrane containing bovine hemoglobin (Hb) as an oxygen carrier was prepared, and oxygen permeation through the membrane was measured by the electrochemical reduction of the permeated oxygen. The oxygen permeation was facilitated, as analyzed by a dual-mode model, to give permeation parameters of the membranes such as the diffusion coefficient (DHb) of the mobile carrier Hb and the solution-diffusion coefficient of oxygen (Do2). The facilitated permeation was the product of the Hb concentration ([Hb]0) and DHb in the membrane solution. DHb decreased with [Hb]0 or the solution viscosity; the maximum of the oxygen permeability (6.2 × 10-8 cm3(STP)cm cm-2s-1 cmHg-1 at the feed stream oxygen pressure of 0.54 cmHg) was observed at [Hb]0 = 12.8 g dl-1, where the facilitation factor and the oxygen/nitrogen permselectivity were ca. 10 and 18, respectively.

Original languageEnglish
Pages (from-to)255-259
Number of pages5
JournalBulletin of the Chemical Society of Japan
Issue number1
Publication statusPublished - 1996 Jan

ASJC Scopus subject areas

  • General Chemistry


Dive into the research topics of 'Analysis of Facilitated Oxygen Transport in a Liquid Membrane of Hemoglobin'. Together they form a unique fingerprint.

Cite this