Anti-hyperglycemic activity of kiwifruit leaf (Actinidia deliciosa) in mice

Miyuki Shirosaki, Tomoyuki Koyama*, Kazunaga Yazawa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


The methanol extract of kiwifruit leaf suppressed the postprandial blood glucose level after an oral administration of soluble starch or sucrose in mice. The mechanism of action is proposed to be due to the α-amylase-inhibiting activity in the 90% aqueous methanol fraction and α-glucosidase- inhibiting activity in the n-buthanol fraction, based on the results of in vitro experiments.

Original languageEnglish
Pages (from-to)1099-1102
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Issue number4
Publication statusPublished - 2008
Externally publishedYes


  • α-amylase-inhibiting activity
  • α-glucosidase-inhibiting activity
  • Leaf of kiwifruit Actinidia deliciosa
  • Preventive food for diabetes

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Chemistry (miscellaneous)
  • Applied Microbiology and Biotechnology
  • Food Science


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