TY - JOUR
T1 - Assessment of harmfulness and biological effect of carbon fiber dust generated during new carbon fiber recycling method
AU - Moriyama, Akihiro
AU - Hasegawa, Takema
AU - Nagaya, Chisato
AU - Hamada, Kazuhiro
AU - Himaki, Takehiro
AU - Murakami, Mami
AU - Horie, Masanori
AU - Takahashi, Junko
AU - Iwahashi, Hitoshi
AU - Moritomi, Hiroshi
N1 - Funding Information:
We thank Prof. Tomonori Iwama and Prof. Tomoyuki Nakagawa for their generous support, valuable suggestions and comments on the manuscript. We would like to thank Editage ( www.editage.jp ) for English language editing. This research was funded by New Energy and Industrial Technology Development Organization of Japan (NEDO) grants “Strategic energy saving technological innovation program (P12004)”.
Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/10/15
Y1 - 2019/10/15
N2 - Concern over the effects of nanomaterials on human health has risen due to the dramatic advances in the development of various technologies based on nanomaterials. Gifu Prefecture and Gifu University are developing technologies for recycling used carbon fiber because the waste disposal process is highly cost and energy intensive. However, generation of carbon fiber dust during the recycling process is a serious issue, especially in the occupational environment. Recycling requires carbonization by partial firing treatment at 500℃ followed by firing treatment at 440℃: these processes produce dust as a by-product. It is important to study the influence of carbon fibers on human health at a molecular level. In this study, three types of carbon fibers - before recycling, after carbonization, and after firing were evaluated for their toxic effects on mice. During the breeding period, no loss in body weight was confirmed. Further, by staining the lung tissue sections, it was found that pulmonary fibrosis did not occur. We found that these carbon fibers might not possess severe toxicity. However, we also found that the toxicity varies according to firing treatment. Furthermore, we found that firing treatment reduces the potential hazard to human health.
AB - Concern over the effects of nanomaterials on human health has risen due to the dramatic advances in the development of various technologies based on nanomaterials. Gifu Prefecture and Gifu University are developing technologies for recycling used carbon fiber because the waste disposal process is highly cost and energy intensive. However, generation of carbon fiber dust during the recycling process is a serious issue, especially in the occupational environment. Recycling requires carbonization by partial firing treatment at 500℃ followed by firing treatment at 440℃: these processes produce dust as a by-product. It is important to study the influence of carbon fibers on human health at a molecular level. In this study, three types of carbon fibers - before recycling, after carbonization, and after firing were evaluated for their toxic effects on mice. During the breeding period, no loss in body weight was confirmed. Further, by staining the lung tissue sections, it was found that pulmonary fibrosis did not occur. We found that these carbon fibers might not possess severe toxicity. However, we also found that the toxicity varies according to firing treatment. Furthermore, we found that firing treatment reduces the potential hazard to human health.
KW - Carbon fiber
KW - DNA microarray
KW - Safety assessment
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U2 - 10.1016/j.jhazmat.2019.120777
DO - 10.1016/j.jhazmat.2019.120777
M3 - Article
C2 - 31228707
AN - SCOPUS:85067392460
SN - 0304-3894
VL - 378
JO - Journal of Hazardous Materials
JF - Journal of Hazardous Materials
M1 - 120777
ER -