TY - JOUR
T1 - Association between mental health and arterial stiffness in middle-aged and older adults
AU - Akazawa, Nobuhiko
AU - Tanahashi, Koichiro
AU - Kosaki, Keisei
AU - Ai Hamasaki, Seiji Maeda
N1 - Funding Information:
This work was supported by The Japan Society for the Promotion of Science KAKENHI, Grand Number 16K16594.
Publisher Copyright:
© 2020 Association for Research into Arterial Structure and Physiology. Publishing services by Atlantis Press International B.V.
PY - 2020/12
Y1 - 2020/12
N2 - Background: Mental stress is a risk factor for cardiovascular disease. However, little is known about the impact of mental stress on arterial function in middle-aged and older adults. Objective: This study is aimed to investigate the association between mental stress and arterial function in this population. Methods: A total of 156 healthy middle-aged and older adults (aged 50-79 years) participated in this study. Mental stress was evaluated by the General Health Questionnaire (GHQ), and arterial stiffness was measured by the Carotid-femoral Pulse Wave Velocity (cfPWV). Results: cfPWV was significantly correlated with the GHQ score, even after adjustment for age, sex, body mass index, and cholesterol, triglyceride, and glucose. Multiple regression analysis further indicated that GHQ score was a significantly independent determinant of cfPWV (p < 0.05). Conclusion: GHQ is positively associated with arterial stiffness, independent of the potential confounding factors in healthy middle-aged and older adults.
AB - Background: Mental stress is a risk factor for cardiovascular disease. However, little is known about the impact of mental stress on arterial function in middle-aged and older adults. Objective: This study is aimed to investigate the association between mental stress and arterial function in this population. Methods: A total of 156 healthy middle-aged and older adults (aged 50-79 years) participated in this study. Mental stress was evaluated by the General Health Questionnaire (GHQ), and arterial stiffness was measured by the Carotid-femoral Pulse Wave Velocity (cfPWV). Results: cfPWV was significantly correlated with the GHQ score, even after adjustment for age, sex, body mass index, and cholesterol, triglyceride, and glucose. Multiple regression analysis further indicated that GHQ score was a significantly independent determinant of cfPWV (p < 0.05). Conclusion: GHQ is positively associated with arterial stiffness, independent of the potential confounding factors in healthy middle-aged and older adults.
KW - Elderly
KW - General health questionnaire
KW - Pulse wave velocity
KW - Stress
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U2 - 10.2991/ARTRES.K.200720.001
DO - 10.2991/ARTRES.K.200720.001
M3 - Article
AN - SCOPUS:85104470106
SN - 1872-9312
VL - 26
SP - 223
EP - 227
JO - Artery Research
JF - Artery Research
IS - 4
ER -
