Bioinformatics Approaches for Determining the Functional Impact of Repetitive Elements on Non-coding RNAs

Chao Zeng*, Atsushi Takeda, Kotaro Sekine, Naoki Osato, Tsukasa Fukunaga, Michiaki Hamada

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Citations (Scopus)

Abstract

With a large number of annotated non-coding RNAs (ncRNAs), repetitive sequences are found to constitute functional components (termed as repetitive elements) in ncRNAs that perform specific biological functions. Bioinformatics analysis is a powerful tool for improving our understanding of the role of repetitive elements in ncRNAs. This chapter summarizes recent findings that reveal the role of repetitive elements in ncRNAs. Furthermore, relevant bioinformatics approaches are systematically reviewed, which promises to provide valuable resources for studying the functional impact of repetitive elements on ncRNAs.

Original languageEnglish
Title of host publicationMethods in Molecular Biology
PublisherHumana Press Inc.
Pages315-340
Number of pages26
DOIs
Publication statusPublished - 2022

Publication series

NameMethods in Molecular Biology
Volume2509
ISSN (Print)1064-3745
ISSN (Electronic)1940-6029

Keywords

  • Bioinformatics
  • Functional element
  • ncRNA
  • Non-coding RNA
  • Repetitive element
  • Transposable element

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics

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