BSA and lysozyme adsorption on homoionic montmorillonite: Influence of the interlayer cation

Mathilde Lepoitevin, Maguy Jaber, Régis Guégan, Jean Marc Janot, Philippe Dejardin, François Henn, Sébastien Balme*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)

Abstract

This study aims to investigate the influence of interlayer cation alkali metal series (Li+, Na+, K+, Rb+, Cs+) and alkali earth metal (Mg2+, Ca2+, Ba2+) on adsorption of model proteins (lysozyme and bovine serum albumin). The localizations of both proteins and their conformational modifications in the interlayer space of the natural clay mineral were studied by X-ray diffraction, transmission electronic microscopy and fluorescence experiments. Based on Langmuir model isotherms, a strong influence of interlayer cation on maximum adsorbed amount and adsorption equilibrium constant has been observed. However the usual kosmotrope/chaotrope classification cannot be used to describe protein adsorption.

Original languageEnglish
Pages (from-to)396-402
Number of pages7
JournalApplied Clay Science
Volume95
DOIs
Publication statusPublished - 2014 Jun
Externally publishedYes

Keywords

  • Homoionic-clay
  • Langmuir isotherm
  • Montmorillonite
  • Protein adsorption

ASJC Scopus subject areas

  • Geology
  • Geochemistry and Petrology

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