Abstract
The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets. The ideal case: The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets.
| Original language | English |
|---|---|
| Pages (from-to) | 8960-9009 |
| Number of pages | 50 |
| Journal | Angewandte Chemie - International Edition |
| Volume | 51 |
| Issue number | 36 |
| DOIs | |
| Publication status | Published - 2012 Sept 3 |
| Externally published | Yes |
Keywords
- C-H functionalization
- natural products
- pharmaceuticals
- synthetic methods
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)