Cardiac stimulant action of constituents of Aloe saponaria

Akira Yagi; Shoji Shibata; Itsuo Nishioka; Shuichi Iwadare; Yukisato Ishida

doi:10.1002/jps.2600710705

Cardiac stimulant action of constituents of Aloe saponaria

Akira Yagi^*, Shoji Shibata, Itsuo Nishioka, Shuichi Iwadare, Yukisato Ishida

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

A highly potent cardiotonic substance, calcium isocitrate, was isolated from Aloe saponaria, using solvent partition, nonionic porous resin, and gel permeation chromatographies. Cardiac stimulant activity of synthesized stereoisomers of calcium isocitrate was demonstrated in isolated guinea pig atria.

Original language	English
Pages (from-to)	739-741
Number of pages	3
Journal	Journal of Pharmaceutical Sciences
Volume	71
Issue number	7
DOIs	https://doi.org/10.1002/jps.2600710705
Publication status	Published - 1982 Jul
Externally published	Yes

Keywords

Aloe Saponaria—cardiac stimulation activity of various constituents, calcium isocitrate
Stereoisomers—synthesis of calcium isocitrate stereoisomers, cardiac stimulation activity, rats, rabbits, guinea pigs
calcium isocitrate—isolated from Aloe saponaria, cardiac stimulation of rabbit and rat, and guinea pig atria

ASJC Scopus subject areas

Pharmaceutical Science

Access to Document

10.1002/jps.2600710705

Cite this

@article{3a8001866b784c4bb9a7f92fdbe2a163,

title = "Cardiac stimulant action of constituents of Aloe saponaria",

abstract = "A highly potent cardiotonic substance, calcium isocitrate, was isolated from Aloe saponaria, using solvent partition, nonionic porous resin, and gel permeation chromatographies. Cardiac stimulant activity of synthesized stereoisomers of calcium isocitrate was demonstrated in isolated guinea pig atria.",

keywords = "Aloe Saponaria—cardiac stimulation activity of various constituents, calcium isocitrate, Stereoisomers—synthesis of calcium isocitrate stereoisomers, cardiac stimulation activity, rats, rabbits, guinea pigs, calcium isocitrate—isolated from Aloe saponaria, cardiac stimulation of rabbit and rat, and guinea pig atria",

author = "Akira Yagi and Shoji Shibata and Itsuo Nishioka and Shuichi Iwadare and Yukisato Ishida",

year = "1982",

month = jul,

doi = "10.1002/jps.2600710705",

language = "English",

volume = "71",

pages = "739--741",

journal = "Journal of Pharmaceutical Sciences",

issn = "0022-3549",

publisher = "John Wiley and Sons Inc.",

number = "7",

}

TY - JOUR

T1 - Cardiac stimulant action of constituents of Aloe saponaria

AU - Yagi, Akira

AU - Shibata, Shoji

AU - Nishioka, Itsuo

AU - Iwadare, Shuichi

AU - Ishida, Yukisato

PY - 1982/7

Y1 - 1982/7

N2 - A highly potent cardiotonic substance, calcium isocitrate, was isolated from Aloe saponaria, using solvent partition, nonionic porous resin, and gel permeation chromatographies. Cardiac stimulant activity of synthesized stereoisomers of calcium isocitrate was demonstrated in isolated guinea pig atria.

AB - A highly potent cardiotonic substance, calcium isocitrate, was isolated from Aloe saponaria, using solvent partition, nonionic porous resin, and gel permeation chromatographies. Cardiac stimulant activity of synthesized stereoisomers of calcium isocitrate was demonstrated in isolated guinea pig atria.

KW - Aloe Saponaria—cardiac stimulation activity of various constituents, calcium isocitrate

KW - Stereoisomers—synthesis of calcium isocitrate stereoisomers, cardiac stimulation activity, rats, rabbits, guinea pigs

KW - calcium isocitrate—isolated from Aloe saponaria, cardiac stimulation of rabbit and rat, and guinea pig atria

UR - http://www.scopus.com/inward/record.url?scp=0019950370&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019950370&partnerID=8YFLogxK

U2 - 10.1002/jps.2600710705

DO - 10.1002/jps.2600710705

M3 - Article

C2 - 7120054

AN - SCOPUS:0019950370

SN - 0022-3549

VL - 71

SP - 739

EP - 741

JO - Journal of Pharmaceutical Sciences

JF - Journal of Pharmaceutical Sciences

IS - 7

ER -

Cardiac stimulant action of constituents of Aloe saponaria

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this