Case of acute zonal occult outer retinopathy resembling retrobulbar optic neuropathy

Manabu Ogawa, Hiroshi Mori, Nobuyuki Nemoto, Motohiro Kiyosawa*, Manabu Mochizuki, Keiko Momose, Masato Wakakura, Hisao Ohde

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


We report a case of acute zonal occult outer retinopathy (AZOOR) with a central scotoma and normal fundus. A 17-year-old man presented with reduced vision in his right eye. A relative afferent pupillary defect was not present, and his fundi were normal. He had a central scotoma in the right eye, but the left eye was normal. Central flicker fusion and color vision were normal in both eyes. Fluorescein angiography showed a somewhat mottled retina in the midperiphery of the right eye. The visually evoked potentials were reduced bilaterally. The a- and b-waves of the photopic ERGs and the amplitude of the flicker ERGs were reduced. In addition, the multifocal electroretinograms (mERGs) were reduced. A diagnosis of AZOOR was made. Electrophysiological studies were helpful in making a diagnosis of AZOOR in this case.

Original languageEnglish
Pages (from-to)217-222
Number of pages6
Issue number4
Publication statusPublished - 2001 Dec 1
Externally publishedYes


  • Acute zonal occult outer retinopathy
  • Central scotoma
  • Multifocal electroretinogram
  • Optic neuropathy
  • Visual evoked potentials

ASJC Scopus subject areas

  • Ophthalmology
  • Clinical Neurology


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