Catalytic intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes for the synthesis of cyclic peptides

Shuhei Obinata; Yu ki Tahara; Kyalo Stephen Kanyiva; Takanori Shibata

doi:10.3987/COM-16-S(S)83

Catalytic intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes for the synthesis of cyclic peptides

Shuhei Obinata, Yu ki Tahara, Kyalo Stephen Kanyiva, Takanori Shibata^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Rhodium-catalyzed intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes gave cyclic peptides in moderate to excellent yields. This is a new catalytic protocol for the synthesis of cyclic peptides containing various amino acids.

Original language	English
Pages (from-to)	1121-1131
Number of pages	11
Journal	Heterocycles
Volume	95
Issue number	2
DOIs	https://doi.org/10.3987/COM-16-S(S)83
Publication status	Published - 2017

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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10.3987/COM-16-S(S)83

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title = "Catalytic intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes for the synthesis of cyclic peptides",

abstract = "Rhodium-catalyzed intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes gave cyclic peptides in moderate to excellent yields. This is a new catalytic protocol for the synthesis of cyclic peptides containing various amino acids.",

author = "Shuhei Obinata and Tahara, {Yu ki} and Kanyiva, {Kyalo Stephen} and Takanori Shibata",

note = "Funding Information: This work was supported by ACT-C from JST (Japan) and Waseda University Grant for Special Research Publisher Copyright: {\textcopyright} 2017 The Japan Institute of Heterocyclic Chemistry.",

year = "2017",

doi = "10.3987/COM-16-S(S)83",

language = "English",

volume = "95",

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T1 - Catalytic intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes for the synthesis of cyclic peptides

AU - Obinata, Shuhei

AU - Tahara, Yu ki

AU - Kanyiva, Kyalo Stephen

AU - Shibata, Takanori

PY - 2017

Y1 - 2017

N2 - Rhodium-catalyzed intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes gave cyclic peptides in moderate to excellent yields. This is a new catalytic protocol for the synthesis of cyclic peptides containing various amino acids.

AB - Rhodium-catalyzed intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes gave cyclic peptides in moderate to excellent yields. This is a new catalytic protocol for the synthesis of cyclic peptides containing various amino acids.

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VL - 95

SP - 1121

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JO - Heterocycles

JF - Heterocycles

IS - 2

ER -

Catalytic intramolecular [2+2+2] cycloaddition of peptide-tethered branched triynes for the synthesis of cyclic peptides

Abstract

ASJC Scopus subject areas

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