Catalytically active species for CeCi3-induced DNA hydrolysis

Makoto Komiyama; Teruyuki Kodama; Naoya Takeda; Jun Sumaoka; Tetsuro Shiiba; Yoichi Matsumoto; Morio Yashiro

doi:10.1093/oxfordjournals.jbchem.a124419

Catalytically active species for CeCi₃-induced DNA hydrolysis

Makoto Komiyama^*, Teruyuki Kodama, Naoya Takeda, Jun Sumaoka, Tetsuro Shiiba, Yoichi Matsumoto, Morio Yashiro

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

Cerium(III) chloride efficiently hydrolyzes DNA at pH 7 under aerobic conditions. A titration study showed that Ce(III) is oxidized to Ce(IV) in the reaction mixture and the resultant Ce(IV) is responsible for the DNA hydrolysis.

Original language	English
Pages (from-to)	809-810
Number of pages	2
Journal	Journal of biochemistry
Volume	115
Issue number	5
DOIs	https://doi.org/10.1093/oxfordjournals.jbchem.a124419
Publication status	Published - 1994 May
Externally published	Yes

Keywords

Artificial restriction enzyme
Ce(IV) ion
Cerium(III) chloride
DNA hydrolysis

ASJC Scopus subject areas

Biochemistry
Molecular Biology

Access to Document

10.1093/oxfordjournals.jbchem.a124419

Cite this

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title = "Catalytically active species for CeCi3-induced DNA hydrolysis",

abstract = "Cerium(III) chloride efficiently hydrolyzes DNA at pH 7 under aerobic conditions. A titration study showed that Ce(III) is oxidized to Ce(IV) in the reaction mixture and the resultant Ce(IV) is responsible for the DNA hydrolysis.",

keywords = "Artificial restriction enzyme, Ce(IV) ion, Cerium(III) chloride, DNA hydrolysis",

author = "Makoto Komiyama and Teruyuki Kodama and Naoya Takeda and Jun Sumaoka and Tetsuro Shiiba and Yoichi Matsumoto and Morio Yashiro",

year = "1994",

month = may,

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journal = "Journal of Biochemistry",

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T1 - Catalytically active species for CeCi3-induced DNA hydrolysis

AU - Komiyama, Makoto

AU - Kodama, Teruyuki

AU - Takeda, Naoya

AU - Sumaoka, Jun

AU - Shiiba, Tetsuro

AU - Matsumoto, Yoichi

AU - Yashiro, Morio

PY - 1994/5

Y1 - 1994/5

N2 - Cerium(III) chloride efficiently hydrolyzes DNA at pH 7 under aerobic conditions. A titration study showed that Ce(III) is oxidized to Ce(IV) in the reaction mixture and the resultant Ce(IV) is responsible for the DNA hydrolysis.

AB - Cerium(III) chloride efficiently hydrolyzes DNA at pH 7 under aerobic conditions. A titration study showed that Ce(III) is oxidized to Ce(IV) in the reaction mixture and the resultant Ce(IV) is responsible for the DNA hydrolysis.

KW - Artificial restriction enzyme

KW - Ce(IV) ion

KW - Cerium(III) chloride

KW - DNA hydrolysis

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