Cell cultures on a super water-repellent alkylketene dimer surface

Hu Yan*, Hatsuki Shiga, Etsuro Ito, Kaoru Tsujii

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


The fractal alkylketene dimer (AKD) surface is an artificial super water-repellent one with a high contact angle of 174°, therefore, may provide special surface circumstances for studies of biological cells such as cell cultures. The experimental results indicated that the distribution of F-actin in the astrocytes cultured on the fractal AKD-coated dishes showed the stellate shape, while that in the astrocytes cultured on the poly-L-lysine-coated coverslips showed the formation of long alignment. The morphological change of astrocytes is induced by the fractal AKD surface, and the result suggests that astrocyte differentiation is stimulated by the fractal AKD surface.

Original languageEnglish
Article number00529
Pages (from-to)871-876
Number of pages6
JournalInternational Journal of Nanoscience
Issue number6
Publication statusPublished - 2006 Dec
Externally publishedYes


  • Astrocytes
  • Cell culture
  • Fractal structure
  • Glial cell
  • Super water-repellency

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • General Materials Science
  • Condensed Matter Physics
  • Computer Science Applications
  • Electrical and Electronic Engineering


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