Cell patterning and navigation of cell migration on caged cell-culturing substrate

Jun Nakanishi*, Yukiko Kikuchi, Tohru Takarada, Hidekazu Nakayama, Kazuo Yamaguchi, Mizuo Maeda

*Corresponding author for this work

Research output: Contribution to conferencePaperpeer-review


Caged cell-culturing substrate is composed of a glass substrate immobilized with a monolayer having a photocleavable protecting group. This substrate can be activated for cell adhesion by illumination of light. By using this substrate, we have succeeded in micropatterning of cells corresponding to photomasks inserted at the location of the field diaphragm of a standard fluorescence microscope. In the present study, we evaluated the effect of terminal functional groups in caged cell-culturing substrates on photoactivation of cell adhesion without using fibronectin. In addition, we applied one of the substrates to navigate migration of single cells from their original pattern by illumination of light.

Original languageEnglish
Number of pages2
Publication statusPublished - 2005
Event54th SPSJ Symposium on Macromolecules - Yamagata, Japan
Duration: 2005 Sept 202005 Sept 22


Other54th SPSJ Symposium on Macromolecules


  • Caged compounds
  • Cell adhesion
  • Cell migration
  • Light
  • Monolayer
  • Patterning

ASJC Scopus subject areas

  • General Engineering


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