Changes in heart rate with refeeding in anorexia nervosa: A pilot study

Nahoko (Miyasaka) Yoshida; Kazuhiro Yoshiuchi; Hiroaki Kumano; Tadashi Sasaki; Tomifusa Kuboki

doi:10.1016/j.jpsychores.2006.02.009

Changes in heart rate with refeeding in anorexia nervosa: A pilot study

Nahoko (Miyasaka) Yoshida^*, Kazuhiro Yoshiuchi, Hiroaki Kumano, Tadashi Sasaki, Tomifusa Kuboki

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

23 Citations (Scopus)

Abstract

Objective: To find differences in heart rate before and after refeeding and to identify which parameters of autonomic activity and endocrine function are associated with these differences. Methods: Before and after the start of refeeding, body weight, RR interval (RRI), heart rate variability, endocrine function, and energy expenditure were measured in nine female anorexia nervosa patients. Results: After short-term refeeding, mean daytime heart rate rose from 54.9 to 69.4 bpm (P<.05). The changes in sympathetic activity were correlated negatively with the changes in RRI (r=-.933, P<.001). Urine C-peptide, IGF-1, and fT3 increased significantly, and norepinephrine tended to increase. Conclusion: We demonstrated that autonomic nervous activity was relevant to changes in heart rate during refeeding, and it is speculated that the increases in insulin secretion, thyroid function, and IGF-1 were responsible for the mechanisms.

Original language	English
Pages (from-to)	571-575
Number of pages	5
Journal	Journal of Psychosomatic Research
Volume	61
Issue number	4
DOIs	https://doi.org/10.1016/j.jpsychores.2006.02.009
Publication status	Published - 2006 Oct 1
Externally published	Yes

Keywords

Anorexia nervosa
Heart rate
Parasympathetic activity
Refeeding
Sympathetic nervous activity

ASJC Scopus subject areas

Clinical Psychology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.jpsychores.2006.02.009

Cite this

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title = "Changes in heart rate with refeeding in anorexia nervosa: A pilot study",

abstract = "Objective: To find differences in heart rate before and after refeeding and to identify which parameters of autonomic activity and endocrine function are associated with these differences. Methods: Before and after the start of refeeding, body weight, RR interval (RRI), heart rate variability, endocrine function, and energy expenditure were measured in nine female anorexia nervosa patients. Results: After short-term refeeding, mean daytime heart rate rose from 54.9 to 69.4 bpm (P<.05). The changes in sympathetic activity were correlated negatively with the changes in RRI (r=-.933, P<.001). Urine C-peptide, IGF-1, and fT3 increased significantly, and norepinephrine tended to increase. Conclusion: We demonstrated that autonomic nervous activity was relevant to changes in heart rate during refeeding, and it is speculated that the increases in insulin secretion, thyroid function, and IGF-1 were responsible for the mechanisms.",

keywords = "Anorexia nervosa, Heart rate, Parasympathetic activity, Refeeding, Sympathetic nervous activity",

author = "Yoshida, {Nahoko (Miyasaka)} and Kazuhiro Yoshiuchi and Hiroaki Kumano and Tadashi Sasaki and Tomifusa Kuboki",

year = "2006",

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doi = "10.1016/j.jpsychores.2006.02.009",

language = "English",

volume = "61",

pages = "571--575",

journal = "Journal of Psychosomatic Research",

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T1 - Changes in heart rate with refeeding in anorexia nervosa

T2 - A pilot study

AU - Yoshida, Nahoko (Miyasaka)

AU - Yoshiuchi, Kazuhiro

AU - Kumano, Hiroaki

AU - Sasaki, Tadashi

AU - Kuboki, Tomifusa

PY - 2006/10/1

Y1 - 2006/10/1

N2 - Objective: To find differences in heart rate before and after refeeding and to identify which parameters of autonomic activity and endocrine function are associated with these differences. Methods: Before and after the start of refeeding, body weight, RR interval (RRI), heart rate variability, endocrine function, and energy expenditure were measured in nine female anorexia nervosa patients. Results: After short-term refeeding, mean daytime heart rate rose from 54.9 to 69.4 bpm (P<.05). The changes in sympathetic activity were correlated negatively with the changes in RRI (r=-.933, P<.001). Urine C-peptide, IGF-1, and fT3 increased significantly, and norepinephrine tended to increase. Conclusion: We demonstrated that autonomic nervous activity was relevant to changes in heart rate during refeeding, and it is speculated that the increases in insulin secretion, thyroid function, and IGF-1 were responsible for the mechanisms.

AB - Objective: To find differences in heart rate before and after refeeding and to identify which parameters of autonomic activity and endocrine function are associated with these differences. Methods: Before and after the start of refeeding, body weight, RR interval (RRI), heart rate variability, endocrine function, and energy expenditure were measured in nine female anorexia nervosa patients. Results: After short-term refeeding, mean daytime heart rate rose from 54.9 to 69.4 bpm (P<.05). The changes in sympathetic activity were correlated negatively with the changes in RRI (r=-.933, P<.001). Urine C-peptide, IGF-1, and fT3 increased significantly, and norepinephrine tended to increase. Conclusion: We demonstrated that autonomic nervous activity was relevant to changes in heart rate during refeeding, and it is speculated that the increases in insulin secretion, thyroid function, and IGF-1 were responsible for the mechanisms.

KW - Anorexia nervosa

KW - Heart rate

KW - Parasympathetic activity

KW - Refeeding

KW - Sympathetic nervous activity

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JO - Journal of Psychosomatic Research

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ER -

Changes in heart rate with refeeding in anorexia nervosa: A pilot study

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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