Characteristics of first and second order kernels of visually evoked potentials elicited by pseudorandom stimulation

The characteristics of the first and the second order kernels of the visually evoked potentials (VEPs) elicited by pseudorandom binary sequence (PRBS) stimuli were investigated. VEPs were recorded from six eyes of four normal volunteers. The effects of stimulus luminance on the latency and amplitude of the first and the second order kernels were determined. The temporal interactions of transient VEPs elicited by single and double pulse stimuli were compared with the first and the second order kernels of the PRBS-VEPs. The correlation coefficient between the logarithm of the stimuli luminance (log I) and VEP amplitude of the first order kernels was 0.45 (p < 0.05), and that between log I and P1 latency was -0.62(p < 0.005). The second order kernels were not equal to the temporal interactions of the responses. However, the latency of the negative peak of the fourth slice was similar to the temporal interaction to double pulse stimulation with an inter-stimulus interval of 40 ms. An inhibitory component at 40 ms following the first stimulus was detected in the analysis of both PRBS-VEPs second order kernel and transient VEPs. This function may help to increase the frequency of critical flicker fusion in normal subjects.