Circulating adiponectin levels are associated with peak oxygen uptake in Japanese

Nobuyuki Miyatake*, Takeyuki Numata, Haruka Murakami, Ryoko Kawakami, Kiyoshi Sanada, Izumi Tabata, Motohiko Miyachi

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)


Objective: The aim of this study was to investigate the link between circulating adiponectin levels and peak oxygen uptake and/or physical activity in Japanese. Methods: A total of 528 subjects (188 men and 340 women) were enrolled in this cross-sectional study. Circulating adiponectin levels, physical activity measured by tri-axial accelerometers, peak oxygen uptake and metabolic risk parameters were evaluated. We also assessed anthropometric factors, blood pressure, blood examinations and energy intake. Results: Circulating adiponectin levels were 6.7 ± 3.0 μg/mL in men and 11.0 ± 4.9 μg/mL in women. Circulating adiponectin levels were positively correlated with physical fitness after adjusting for age, physical activity evaluated by ∑ [metabolic equivalents x h per week (METs h/w)], cigarette smoking habit and energy intake in both sexes. However, these associations were attenuated further after adjusting for body mass index including other confounding factors, especially in men. However, circulating adiponectin levels were not associated with physical activity in either sex. Conclusion: Circulating adiponectin levels were associated with peak oxygen uptake rather than physical activity.

Original languageEnglish
Pages (from-to)279-285
Number of pages7
JournalEnvironmental Health and Preventive Medicine
Issue number4
Publication statusPublished - 2014 Jul
Externally publishedYes


  • Adiponectin
  • Body composition
  • Japanese
  • Peak oxygen uptake
  • Physical activity

ASJC Scopus subject areas

  • Medicine(all)


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