TY - JOUR
T1 - Combined use of two frailty tools in predicting mortality in older adults
AU - Watanabe, Daiki
AU - Yoshida, Tsukasa
AU - Yamada, Yosuke
AU - Watanabe, Yuya
AU - Yamada, Minoru
AU - Fujita, Hiroyuki
AU - Miyachi, Motohiko
AU - Arai, Hidenori
AU - Kimura, Misaka
N1 - Funding Information:
We would like to express our appreciation to all participants of this study and to all individuals involved in the data collection. We acknowledge several administrative of Kameoka city and Kyoto prefecture. We would like to thank the Kyoto–Kameoka Study Group who contributed their resources to the development of this study. We would like to thank Editage ( www.editage.jp ) for the English-language editing. The Kyoto-Kameoka study was conducted with JSPS KAKENHI and was supported by a research grant provided to Misaka Kimura (24240091), Yosuke Yamada (15H05363), and Daiki Watanabe (21K17699); a grant and administrative support by the Kyoto Prefecture Community-based Integrated older adults Care Systems Promotion Organization since 2011; Kameoka City under the program of the Long-term Care Insurance and Planning Division of the Health and Welfare Bureau for the older adults, Ministry of Health, Labor, and Welfare and the World Health Organization (WHO) Collaborating Centre on Community Safety Promotion. The Article Processing Charges was supported by Health and Labor Sciences Research Grant provided to Motohiko Miyachi (22AC5004 and 21FA1004).
Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - We aimed to verify the combined use of two frailty tools in predicting mortality in older adults. We used the data of 10,276 Japanese older adults (aged ≥ 65 years) who provided valid responses to two frailty assessment tools in a mail survey in Japan’s Kyoto‒Kameoka Prospective cohort study. Frailty status was categorized into four groups depending on the validated frailty screening index and Kihon Checklist, respectively: Non-frailty (n = 5960), Physical frailty (n = 223), Comprehensive frailty (n = 2211), and Combination (n = 1882) groups. Mortality data were collected between July 30, 2011, and November 30, 2016. We assessed the relationship between frailty status and all-cause mortality risk using multivariate Cox proportional hazards models. During a median follow-up of 5.3 years, we recorded 1257 deaths. After adjusting for confounders, the Combination group had the highest mortality risk compared with the other groups [Non-frailty: reference; Physical frailty: hazards ratio [HR], 0.99 (95% confidence interval [CI] 0.58 to 1.70); Comprehensive frailty: 1.91 (1.63 to 2.23); Combination: 2.85 (2.44 to 3.22)]. People who are positive for frailty in both instruments have a higher risk of death than those who are positive to one model.
AB - We aimed to verify the combined use of two frailty tools in predicting mortality in older adults. We used the data of 10,276 Japanese older adults (aged ≥ 65 years) who provided valid responses to two frailty assessment tools in a mail survey in Japan’s Kyoto‒Kameoka Prospective cohort study. Frailty status was categorized into four groups depending on the validated frailty screening index and Kihon Checklist, respectively: Non-frailty (n = 5960), Physical frailty (n = 223), Comprehensive frailty (n = 2211), and Combination (n = 1882) groups. Mortality data were collected between July 30, 2011, and November 30, 2016. We assessed the relationship between frailty status and all-cause mortality risk using multivariate Cox proportional hazards models. During a median follow-up of 5.3 years, we recorded 1257 deaths. After adjusting for confounders, the Combination group had the highest mortality risk compared with the other groups [Non-frailty: reference; Physical frailty: hazards ratio [HR], 0.99 (95% confidence interval [CI] 0.58 to 1.70); Comprehensive frailty: 1.91 (1.63 to 2.23); Combination: 2.85 (2.44 to 3.22)]. People who are positive for frailty in both instruments have a higher risk of death than those who are positive to one model.
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U2 - 10.1038/s41598-022-19148-x
DO - 10.1038/s41598-022-19148-x
M3 - Article
C2 - 36057638
AN - SCOPUS:85137159545
SN - 2045-2322
VL - 12
JO - Scientific reports
JF - Scientific reports
IS - 1
M1 - 15042
ER -