Complete nucleotide sequence of pLD-TEX-KL, a 66-kb plasmid of Legionella dumoffii TEX-KL strain

Tian Qin*, Hideki Hirakawa, Ken ichiro Iida, Kenshiro Oshima, Masahira Hattori, Kosuke Tashiro, Satoru Kuhara, Shin ichi Yoshida

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The complete nucleotide sequence of a large (66 kb) plasmid pLD-TEX-KL of Legionella dumoffii TEX-KL strain was determined. Of the 57 predicted open reading frames (ORFs), 39 (68%) encoded proteins similar to previously known proteins, five (9%) were assigned with putative functions, three (5%) encoded conserved hypothetical proteins, and 10 (18%) had no homology to any genes present in the current open databases. The ORFs with similar functions were organized in a modular structure; thus, transfer region was identified, as well as a putative heavy-metal ion transporter system (hel). The transfer region encoded homologs of the Salmonella entrica serovar Typhi conjugative system components involved in conjugation. In addition, we also found a potential protein that was analogous to the DNA polymerase III epsilon subunit. It is rarely found that plasmid encode the DNA polymerase.

Original languageEnglish
Pages (from-to)261-268
Number of pages8
JournalPlasmid
Volume58
Issue number3
DOIs
Publication statusPublished - 2007 Nov
Externally publishedYes

Keywords

  • Complete nucleotide sequence
  • Legionella dumoffii
  • Plasmid

ASJC Scopus subject areas

  • Molecular Biology

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