Complete nucleotide sequence of the Japanese encephalitis virus genome RNA

Hideo Sumiyoshi; Chisato Mori; Isao Fuke; Kouichi Morita; Satoshi Kuhara; Jun Kondou; Yo Kikuchi; Hiroshi Nagamatu; Akira Igarashi

doi:10.1016/0042-6822(87)90144-9

Complete nucleotide sequence of the Japanese encephalitis virus genome RNA

Hideo Sumiyoshi^*, Chisato Mori, Isao Fuke, Kouichi Morita, Satoshi Kuhara, Jun Kondou, Yo Kikuchi, Hiroshi Nagamatu, Akira Igarashi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

171 Citations (Scopus)

Abstract

The complete nucleotide sequence of the Japanese encephalitis virus (JEV) genome RNA was determined. The JEV genome contains 10,976 nucleotides and encodes a single long open reading frame (ORF) of 10,296 nucleotides corresponding to 3432 amino acid residues. This long polypeptide is thought to be cleaved into three structural proteins and several nonstructural proteins of the virus. The genetic location of the three structural proteins was determined by comparing the deduced amino acid sequence from the nucleotide sequence with the N-terminal amino acid sequences that were determined from the three purified structural proteins. The C-terminal region of the ORF may encode an RNA-dependent RNA polymerase which has significant sequence homology with those of other RNA viruses.

Original language	English
Pages (from-to)	497-510
Number of pages	14
Journal	Virology
Volume	161
Issue number	2
DOIs	https://doi.org/10.1016/0042-6822(87)90144-9
Publication status	Published - 1987
Externally published	Yes

ASJC Scopus subject areas

Virology
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0042-6822(87)90144-9

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abstract = "The complete nucleotide sequence of the Japanese encephalitis virus (JEV) genome RNA was determined. The JEV genome contains 10,976 nucleotides and encodes a single long open reading frame (ORF) of 10,296 nucleotides corresponding to 3432 amino acid residues. This long polypeptide is thought to be cleaved into three structural proteins and several nonstructural proteins of the virus. The genetic location of the three structural proteins was determined by comparing the deduced amino acid sequence from the nucleotide sequence with the N-terminal amino acid sequences that were determined from the three purified structural proteins. The C-terminal region of the ORF may encode an RNA-dependent RNA polymerase which has significant sequence homology with those of other RNA viruses.",

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AU - Sumiyoshi, Hideo

AU - Mori, Chisato

AU - Fuke, Isao

AU - Morita, Kouichi

AU - Kuhara, Satoshi

AU - Kondou, Jun

AU - Kikuchi, Yo

AU - Nagamatu, Hiroshi

AU - Igarashi, Akira

PY - 1987

Y1 - 1987

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AB - The complete nucleotide sequence of the Japanese encephalitis virus (JEV) genome RNA was determined. The JEV genome contains 10,976 nucleotides and encodes a single long open reading frame (ORF) of 10,296 nucleotides corresponding to 3432 amino acid residues. This long polypeptide is thought to be cleaved into three structural proteins and several nonstructural proteins of the virus. The genetic location of the three structural proteins was determined by comparing the deduced amino acid sequence from the nucleotide sequence with the N-terminal amino acid sequences that were determined from the three purified structural proteins. The C-terminal region of the ORF may encode an RNA-dependent RNA polymerase which has significant sequence homology with those of other RNA viruses.

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Complete nucleotide sequence of the Japanese encephalitis virus genome RNA

Abstract

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UN SDGs

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