Concise synthesis of 6-formylindolo[3,2-b]carbazole (FICZ)

Daisuke Sekine, Shota Okeda, Seijiro Hosokawa*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


A concise synthesis of 6-formylindolo[3,2-b]carbazole (FICZ), a potent ligand of the aryl hydrocarbon receptor (AhR), has been established. The conjugate addition of the enolate derived from indolylacetate 2 to 2-chloro-3-formylindole 3 was accomplished. The following cyclization reaction under the acidic conditions gave the indolo[3,2-b]carbazole skeleton.

Original languageEnglish
Pages (from-to)1932-1934
Number of pages3
JournalChemistry Letters
Issue number12
Publication statusPublished - 2014

ASJC Scopus subject areas

  • Chemistry(all)


Dive into the research topics of 'Concise synthesis of 6-formylindolo[3,2-b]carbazole (FICZ)'. Together they form a unique fingerprint.

Cite this