Abstract
A concise and straightforward synthesis of 2,4,6-trimethyloctanoates was established by using the sequence of the vinylogous Mukaiyama aldol reaction and regio- and stereoselective reduction reactions. All isomers were obtained selectively in a few steps. The short step synthesis of septoriamycin A, an antimalarial and antileishmanial agent, has been achieved by this methodology.
Original language | English |
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Pages (from-to) | 3170-3173 |
Number of pages | 4 |
Journal | Organic Letters |
Volume | 15 |
Issue number | 12 |
DOIs | |
Publication status | Published - 2013 Jun 21 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry