Context-based segmentation of renal corpuscle from microscope renal biopsy image sequence

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2 Citations (Scopus)


A renal biopsy is a procedure to get a small piece of kidney for microscopic examination. With the development of tissue sectioning and medical imaging techniques, microscope renal biopsy image sequences are consequently obtained for computer-aided diagnosis. This paper proposes a new context-based segmentation algorithm for acquired image sequence, in which an improved genetic algorithm (GA) patching method is developed to segment different size target. To guarantee the correctness of first image segmentation and facilitate the use of context information, a boundary fusion operation and a simplified scale-invariant feature transform (SIFT)-based registration are presented respectively. The experimental results show the proposed segmentation algorithm is effective and accurate for renal biopsy image sequence.

Original languageEnglish
Pages (from-to)1114-1121
Number of pages8
JournalIEICE Transactions on Fundamentals of Electronics, Communications and Computer Sciences
Issue number5
Publication statusPublished - 2015 May 1


  • Computer-aided diagnosis
  • Genetic algorithm
  • Microscope image
  • Registration
  • Segmentation

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Computer Graphics and Computer-Aided Design
  • Applied Mathematics
  • Signal Processing


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