Current rectification with poly-L-lysine-coated quartz nanopipettes

Senkei Umehara, Nader Pourmand, Chris D. Webb, Ronald W. Davis, Kenji Yasuda, Miloslav Karhanek*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

183 Citations (Scopus)


Ion current rectification with quartz nanopipette electrodes was investigated through the control of the surface charge. The presence and absence of a positively charged poly-L-lysine (PLL) coating resulted in the rectified current with opposite polarity. The results agreed with the theories developed for current-rectifying conical nanopores, suggesting the similar underlying mechanism among asymmetric nanostructure in general. This surface condition dependence can be used as the fundamental principle of multi-purpose real-time in vivo biosensors.

Original languageEnglish
Pages (from-to)2486-2492
Number of pages7
JournalNano Letters
Issue number11
Publication statusPublished - 2006 Nov
Externally publishedYes

ASJC Scopus subject areas

  • Bioengineering
  • General Chemistry
  • General Materials Science
  • Condensed Matter Physics
  • Mechanical Engineering


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