TY - GEN
T1 - Development of a compact mock circulation system and a new flow-cell model for pulse spectrophotometry
AU - Oura, M.
AU - Kobayashi, N.
AU - Takeda, S.
AU - Iwasaki, K.
AU - Umezu, Mitsuo
PY - 2008
Y1 - 2008
N2 - We have developed an extremely compact mock circulation system. This system can simulate artery blood circulation and generate a pulse wave with a very small amount of blood. We were also able to measure the in vitro pulsatile optical density ratio (Φvt) using this system with a flow cell [1]. Results showed a difference between Φvt and the in vivo pulsatile optical density ratio (Φvi) for the same oxygen saturations. To explain this difference, we proposed a new flow-cell model that includes venous flow and arterial flow. Because these systems can simulate the in vivo environment with very accurately, they can be applied to various pulse spectrophotometry studies. Moreover, the required blood volume is very small so the system can evaluate artificial blood or artificial red cells at very low cost. Thus, this system can reduce the time and cost of developing new pulse photometry techniques and other medical equipment.
AB - We have developed an extremely compact mock circulation system. This system can simulate artery blood circulation and generate a pulse wave with a very small amount of blood. We were also able to measure the in vitro pulsatile optical density ratio (Φvt) using this system with a flow cell [1]. Results showed a difference between Φvt and the in vivo pulsatile optical density ratio (Φvi) for the same oxygen saturations. To explain this difference, we proposed a new flow-cell model that includes venous flow and arterial flow. Because these systems can simulate the in vivo environment with very accurately, they can be applied to various pulse spectrophotometry studies. Moreover, the required blood volume is very small so the system can evaluate artificial blood or artificial red cells at very low cost. Thus, this system can reduce the time and cost of developing new pulse photometry techniques and other medical equipment.
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U2 - 10.1109/iembs.2008.4649241
DO - 10.1109/iembs.2008.4649241
M3 - Conference contribution
C2 - 19162744
AN - SCOPUS:61849101438
SN - 9781424418152
T3 - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08 - "Personalized Healthcare through Technology"
SP - 670
EP - 673
BT - Proceedings of the 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
PB - IEEE Computer Society
T2 - 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'08
Y2 - 20 August 2008 through 25 August 2008
ER -