TY - JOUR
T1 - Development of an APD-based PET module and preliminary resolution performance of an experimental prototype gantry
AU - Kataoka, Jun
AU - Matsuda, Hidenori
AU - Nishikido, Fumihiko
AU - Koizumi, Makoto
AU - Ikeda, Hirokazu
AU - Yoshino, Masao
AU - Miura, Takamasa
AU - Tanaka, Satoshi
AU - Ishikawa, Yoshitaka
AU - Kawabata, Nobuyuki
AU - Shimizu, Keiji
AU - Matsunaga, Yusuke
AU - Kishimoto, Shunji
AU - Kubo, Hidetoshi
AU - Yanagida, Yoshio
AU - Nakamori, Takeshi
PY - 2010/10
Y1 - 2010/10
N2 - The development of a high-resolution Positron Emission Tomography (PET) technique with sub-millimeter spatial resolution, which utilizes newly designed reverse-type APD-arrays, is uderway. All the detector blocks are modularized with the overall dimension of each module, including the APD array, LYSO scintillator matrix and Front-End Circuits (FECs), which are only 30 × 30 × 80mm3. Each APD device also has a monolithic 16 × 16 pixel structure with an active area of 1.0 mm2 per pixel. The FEC includes two identical analog ASICs specifically designed for APDs with a noise characteristic of 560+30 e-/pF and a timing resolution of 460 ps (rms), respectively. An energy resolution of 13.7 ± 1.1% (FWHM) with 662 keV gamma-rays was measured using the 16 × 16 arrays. At this stage a pair of module and coincidence circuits has been assembled into an experimental prototype gantry. Spatial resolutions of 0.9, 1.4, and 1.3 mm (FWHM) were obtained from FBP reconstructed images in preliminary experiments with a point source positioned centrally, and 1 and 5 mm off-center, respectively. Comparison with a Monte-Carlo simulation of a fully-designed gantry over a wider range of field-of-view showed good correlation with the experimental data. A simple but conceptual design of a DOI configuration is also proposed as a test example of a future APD-PET scanner.
AB - The development of a high-resolution Positron Emission Tomography (PET) technique with sub-millimeter spatial resolution, which utilizes newly designed reverse-type APD-arrays, is uderway. All the detector blocks are modularized with the overall dimension of each module, including the APD array, LYSO scintillator matrix and Front-End Circuits (FECs), which are only 30 × 30 × 80mm3. Each APD device also has a monolithic 16 × 16 pixel structure with an active area of 1.0 mm2 per pixel. The FEC includes two identical analog ASICs specifically designed for APDs with a noise characteristic of 560+30 e-/pF and a timing resolution of 460 ps (rms), respectively. An energy resolution of 13.7 ± 1.1% (FWHM) with 662 keV gamma-rays was measured using the 16 × 16 arrays. At this stage a pair of module and coincidence circuits has been assembled into an experimental prototype gantry. Spatial resolutions of 0.9, 1.4, and 1.3 mm (FWHM) were obtained from FBP reconstructed images in preliminary experiments with a point source positioned centrally, and 1 and 5 mm off-center, respectively. Comparison with a Monte-Carlo simulation of a fully-designed gantry over a wider range of field-of-view showed good correlation with the experimental data. A simple but conceptual design of a DOI configuration is also proposed as a test example of a future APD-PET scanner.
KW - Avalanche photodiode
KW - Depth-Of-Interaction (DOI)
KW - Positron Emission Tomography (PET)
KW - image reconstruction
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U2 - 10.1109/TNS.2010.2055889
DO - 10.1109/TNS.2010.2055889
M3 - Article
AN - SCOPUS:79953309915
SN - 0018-9499
VL - 57
SP - 2448
EP - 2454
JO - IEEE Transactions on Nuclear Science
JF - IEEE Transactions on Nuclear Science
IS - 5 PART 1
M1 - 5559465
ER -