Development of magnetic microbubbles for drug delivery system (DDS)

Kawan Soetanto*, Hiroshi Watarai

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Citations (Scopus)


The purpose of this study is to develop a new ultrasonic contrast agent for the drug delivery system (DDS). Ferromagnetic materials or magnetic carbons were placed on the surfaces of the surfactant microbubbles developed in our laboratory for the above purpose. Multivalent ions such as calcium ions were used to place the ferromagnetic materials or magnetic carbons on the surfaces of the microbubbles. It was confirmed that the developed magnetic microbubbles could be lead by a permanent magnet. Furthermore, the performance of the magnetic microbubbles was evaluated by measuring the time dependence of the attenuation constant as one of their acoustic properties.

Original languageEnglish
Pages (from-to)3230-3232
Number of pages3
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Issue number5 B
Publication statusPublished - 2000
Externally publishedYes


  • Acoustic contrast agent
  • DDS
  • Magnetic carbon
  • Magnetic microbubble
  • Magnetite

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)


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