TY - JOUR
T1 - Different degree of intervention in 6-month weight-loss support and arterial stiffness
T2 - Secondary analysis of a randomized controlled trial
AU - Tanabe, Yoko
AU - Nakata, Yoshio
AU - Zempo-Miyaki, Asako
AU - Hieda, Mutsuko Y.
AU - Choi, Youngju
AU - Fujii, Naoto
AU - Maeda, Seiji
N1 - Funding Information:
This study was supported by the Japan Agriculture Ibaraki Public Welfare Federation and by JSPS KAKENHI [Grant Number 22700689]. This study was also partly funded by the Meiji Yasuda Life Foundation of Health and Welfare.
Publisher Copyright:
© 2020 Asia Oceania Association for the Study of Obesity
PY - 2021/1/1
Y1 - 2021/1/1
N2 - Background and aims: Weight reduction by lifestyle modification (i.e., low-calorie diet and/or exercise) decreases arterial stiffness in overweight or obese individuals. We previously demonstrated that weight loss differs depending on the degree of intervention in weight-loss support in a randomized controlled trial (UMIN000001259). However, the effect of different degrees of intervention on arterial stiffness remains unclear. Methods and results: A total of 188 middle-aged men and women with overweight or obesity (51 ± 7 years, BMI: 29.0 ± 3.2 kg/m2) participated in the 6-month trial wherein they were assigned to a low (LI, n = 63), moderate (MI, n = 62), or high intensive intervention (HI, n = 63) group. Initially, one motivational lecture on weight loss was provided to all three groups, whereas educational materials (textbooks, notebooks, and a pedometer) were provided to groups MI and HI. Additionally, the HI group participated in a series of group-based sessions. Body weight and arterial stiffness assessed by brachial-ankle pulse wave velocity (baPWV) were measured at 0, 3, and 6 months. Six-month weight loss was greater in the order of HI, MI, and LI groups. The interventions reduced baPWV in all groups, and the reduction was not significantly different among the groups (114.3 ± 16.3, 82.6 ± 15.2, and 98.8 ± 90.4 cm/s, respectively). Conclusion: In overweight or obese individuals, different degrees of intervention in weight-loss support affect body weight; however, the extent to which arterial stiffness improves does not differ among support programs.
AB - Background and aims: Weight reduction by lifestyle modification (i.e., low-calorie diet and/or exercise) decreases arterial stiffness in overweight or obese individuals. We previously demonstrated that weight loss differs depending on the degree of intervention in weight-loss support in a randomized controlled trial (UMIN000001259). However, the effect of different degrees of intervention on arterial stiffness remains unclear. Methods and results: A total of 188 middle-aged men and women with overweight or obesity (51 ± 7 years, BMI: 29.0 ± 3.2 kg/m2) participated in the 6-month trial wherein they were assigned to a low (LI, n = 63), moderate (MI, n = 62), or high intensive intervention (HI, n = 63) group. Initially, one motivational lecture on weight loss was provided to all three groups, whereas educational materials (textbooks, notebooks, and a pedometer) were provided to groups MI and HI. Additionally, the HI group participated in a series of group-based sessions. Body weight and arterial stiffness assessed by brachial-ankle pulse wave velocity (baPWV) were measured at 0, 3, and 6 months. Six-month weight loss was greater in the order of HI, MI, and LI groups. The interventions reduced baPWV in all groups, and the reduction was not significantly different among the groups (114.3 ± 16.3, 82.6 ± 15.2, and 98.8 ± 90.4 cm/s, respectively). Conclusion: In overweight or obese individuals, different degrees of intervention in weight-loss support affect body weight; however, the extent to which arterial stiffness improves does not differ among support programs.
KW - Behavioral interventions
KW - Blood pressure
KW - Lifestyle modification
KW - Metabolic syndrome
KW - Obesity
KW - Pulse wave velocity
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U2 - 10.1016/j.orcp.2020.11.006
DO - 10.1016/j.orcp.2020.11.006
M3 - Letter
C2 - 33358148
AN - SCOPUS:85099692520
SN - 1871-403X
VL - 15
SP - 93
EP - 95
JO - Obesity Research and Clinical Practice
JF - Obesity Research and Clinical Practice
IS - 1
ER -
