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Discovery of small-molecule modulator of heterotrimeric Gi-protein by integrated phenotypic profiling and chemical proteomics

  • Tatsuro Kawamura
  • , Yushi Futamura
  • , Erchang Shang
  • , Makoto Muroi
  • , Petra Janning
  • , Masayoshi Ueno
  • , Julian Wilke
  • , Shigeki Takeda
  • , Yasumitsu Kondoh
  • , Slava Ziegler
  • , Nobumoto Watanabe
  • , Herbert Waldmann
  • , Hiroyuki Osada*
  • *Corresponding author for this work

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Biochemistry, Genetics and Molecular Biology

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