Dissociation of aggregated ferroheme complexes and protoporphyrine IX by water-soluble polymers

Hiroyuki Nishide*, Keiji Mihayashi, Eishun Tsuchida

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

THe ferroheme · pyridine complex, ferroheme and protoporphyrin IX form the aggregates by the hydrophobic interaction in aqueous solutions. We found by spectrophotometric and fluorometric measurements that the aggregates dissociated into the monomers by the addition of water-soluble polymers, such as, poly(ethyleneoxide), poly(vinylalcohol), poly(vinylpyrrolidone) and poly(styrene sulfonate). The dissociation by the polymers proceeded as their hydrophobicities increased. The aggregated ferroheme was effectively dissociated by the copolymers of 4-vinylpyridine which were water-soluble polymer-ligands.

Original languageEnglish
Pages (from-to)208-214
Number of pages7
JournalBBA - General Subjects
Volume498
Issue number1
DOIs
Publication statusPublished - 1977 Jun 23

ASJC Scopus subject areas

  • Biochemistry
  • Biophysics
  • Molecular Biology
  • Medicine(all)

Fingerprint

Dive into the research topics of 'Dissociation of aggregated ferroheme complexes and protoporphyrine IX by water-soluble polymers'. Together they form a unique fingerprint.

Cite this