Distribution of parvalbumin immunoreactivity in the human brain

Toshio Ohshima, Toyoshi Endo, Toshimasa Onaya*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)


The cellular distribution of parvalbumin-like immunoreactivity (PA-LI) in the human brain was investigated by peroxidase-antiperoxidase methods using antiserum to rat skeletal muscle parvalbumin. PA-LI was present in non-pyramidal neurons of the cerebral cortices, stellate cells, basket cells and Purkinje cells in cerebellar cortices, and neurons of some nuclei in human brain stem; the distribution of PA-LI in human brain was very similar to that in rat brain. These results indicate that PA-LI is widely distributed in a specific subpopulation of neurons of the human brain.

Original languageEnglish
Pages (from-to)320-322
Number of pages3
JournalJournal of Neurology
Issue number6
Publication statusPublished - 1991 Sept
Externally publishedYes


  • Calcium-binding protein
  • Immunohistochemistry
  • Parvalbumin

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology


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