Early detection of bronchial lesions using lung imaging fluorescence endoscope

N. Ikeda*, H. Honda, T. Katsumi, T. Okunaka, K. Furukawa, T. Tsuchida, K. Tanaka, T. Onoda, T. Hirano, M. Saito, N. Kawate, C. Konaka, H. Kato, Y. Ebihara

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Citations (Scopus)


The performance of the Lung Imaging Fluorescence Endoscope (LIFE) system was compared with conventional bronchoscopy in 158 patients: 68 patients with invasive cancer, 42 patients with abnormal sputum cytology findings (12 early cancer and 26 dysplasia), 17 cases with resected lung cancer and 31 smokers with symptoms. The respective results of conventional bronchoscopy and LIFE for detection of dysplasia were; sensitivity 52% and 90% (biopsy basis), 62% and 92% (patient basis). Fluorescence bronchoscopy may be an important adjunct to conventional bronchoscopy to improve the localization of subtle lesions of bronchus.

Original languageEnglish
Pages (from-to)85-90
Number of pages6
JournalDiagnostic and Therapeutic Endoscopy
Issue number2
Publication statusPublished - 1999
Externally publishedYes


  • Dysplasia
  • Early detection
  • Early lung cancer
  • Fluorescence bronchoscopy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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