TY - JOUR
T1 - Effect of an acute bout of endurance exercise on serum 25(OH)D concentrations in young adults
AU - Sun, Xiaomin
AU - Cao, Zhen Bo
AU - Taniguchi, Hirokazu
AU - Tanisawa, Kumpei
AU - Higuchi, Mitsuru
N1 - Funding Information:
Financial Support: This study was supported in part by a Grant-in-Aid for the Global Centers of Excellence Program (Sport Sciences for the Promotion of Active Life to Waseda University) from the Ministry of Education, Culture, Sports, Science, and Technology of Japan (MEXT; to M.H.), a grant from the MEXT-Supported Program for the Strategic Research Foundation at Private Universities (to M.H.), a Grant-in-Aid for Scientific Research (C) from MEXT (to Z.-B.C.), Grant 31571226 from the National Natural Science Foundation of China, and Grant TP2014057 from the Program for Professors of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning.
Publisher Copyright:
Copyright © 2017 Endocrine Society.
PY - 2017
Y1 - 2017
N2 - Context: Regular exercise or high physical activity levels are associated with higher serum 25-hydroxyvitamin D [25(OH)D] concentrations; however, the effect of acute exercise on serum 25(OH)D concentrations remains unclear. Objective: We aimed to clarify whether acute endurance exercise has a direct effect on the circulating 25(OH)D concentrations in young adults. Design and Setting: Exercise intervention trial in an institutional practice. Patients: Twenty young, active adults (males, n = 10; females, n = 10). Interventions: Participants were asked to perform a cycling exercise for 30 minutes at 70% maximal oxygen uptake. Main Outcome Measures: The serum concentrations of 25(OH)D and other blood parameters were assessed before exercise and at 0, 0.5, 1, 3, and 24 hours after exercise. Results: The serum 25(OH)D concentrations were significantly increased not only at 0 (P < 0.01), 1 (P < 0.05), and 3 hours (P < 0.01) after exercise, but they were also increased at 24 hours (P < 0.05) after acute endurance exercise in young adults. A significant sex 3 time interaction effect was observed(P<0.05), and the incremental areas under the curve for the 25(OH)D concentrations were significantly higher in men than in the women (P < 0.01). Conclusions: There is a direct effect of endurance exercise on serum 25(OH)D concentrations. In addition, sex disparity was observed in the serum 25(OH)D response to acute endurance exercise, and the increase in 25(OH)D concentrations was greater in men than in women.
AB - Context: Regular exercise or high physical activity levels are associated with higher serum 25-hydroxyvitamin D [25(OH)D] concentrations; however, the effect of acute exercise on serum 25(OH)D concentrations remains unclear. Objective: We aimed to clarify whether acute endurance exercise has a direct effect on the circulating 25(OH)D concentrations in young adults. Design and Setting: Exercise intervention trial in an institutional practice. Patients: Twenty young, active adults (males, n = 10; females, n = 10). Interventions: Participants were asked to perform a cycling exercise for 30 minutes at 70% maximal oxygen uptake. Main Outcome Measures: The serum concentrations of 25(OH)D and other blood parameters were assessed before exercise and at 0, 0.5, 1, 3, and 24 hours after exercise. Results: The serum 25(OH)D concentrations were significantly increased not only at 0 (P < 0.01), 1 (P < 0.05), and 3 hours (P < 0.01) after exercise, but they were also increased at 24 hours (P < 0.05) after acute endurance exercise in young adults. A significant sex 3 time interaction effect was observed(P<0.05), and the incremental areas under the curve for the 25(OH)D concentrations were significantly higher in men than in the women (P < 0.01). Conclusions: There is a direct effect of endurance exercise on serum 25(OH)D concentrations. In addition, sex disparity was observed in the serum 25(OH)D response to acute endurance exercise, and the increase in 25(OH)D concentrations was greater in men than in women.
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U2 - 10.1210/jc.2017-00146
DO - 10.1210/jc.2017-00146
M3 - Article
C2 - 28973380
AN - SCOPUS:85038028539
SN - 0021-972X
VL - 102
SP - 3937
EP - 3944
JO - Journal of Clinical Endocrinology and Metabolism
JF - Journal of Clinical Endocrinology and Metabolism
IS - 11
ER -