Effect of fructose ingestion before and during prolonged exercise on subsequent maximal exercise performance

Shin Terada, Kazunobu Ohmori, Yoshio Nakamura, Isao Muraoka

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)


The purpose of this study was to examine the effect of fructose ingestion on maximal exercise performance capacity following prolonged steady-state exercise compared with glucose or placebo ingestion, in 7 male college students (age 23.3±0.7 yr, height 171.3±1.9 cm, weight 68.4±1.4 kg, V̇o2max 3.5±0.2 L/min, mean ± SEM). The subjects cycled constantly on an ergometer at 59± 2% V̇o2max for 100 min divided in the middle by a 5-min rest, and then performed 10 min of all-out self-paced cycling. They ingested either 8% fructose solution (F), 8% glucose solution (G) or artificially sweetened placebo (P) before and during exercise (at 20, 40, 65, 85min). Before exercise and at 50 and 100 min of exercise and 5 min after the performance ride, blood samples were collected for determination of the concentrations of blood lactate, serum glucose and serum FFA. In the G trial, the serum FFA level was significantly lower than in the P and F trials at any of the time points during and after exercise (vs. P ; p<0.01, vs. F ; p<0.05). However, glucose ingestion maintained serum glucose at a significantly higher level during and after exercise than placebo ingestion (p< 0.01) and improved the total work output in the 10-min performance ride (G vs. P ; 135± 8 KJ vs. 128± 8 KJ, p<0.05). Although in the F trial, the serum FFA level was elevated during exercise compared to that in the G trial and the serum glucose level was significantly higher than in the P trial (vs. P ; p<0.01), the blood lactate level after exercise was lower than in the G trial and total work output was similar to that in the P trial (123± 8 KJ, vs. G ; p<0.01). These results indicate that fructose ingestion before and during exercise cannot improve the ability to perform high-intensity exercise late in prolonged exercise despite maintaining the serum glucose level.

Original languageEnglish
Pages (from-to)343-352
Number of pages10
Journaljapanese journal of physical fitness and sports medicine
Issue number3
Publication statusPublished - 1999 Jun


  • All-out self-paced performance
  • Fructose ingestion
  • Prolonged exercise
  • Serum FFA
  • Serum glucose

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation


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