Effect of Vitamin D Supplementation on Body Composition and Physical Fitness in Healthy Adults: A Double-Blind, Randomized Controlled Trial

Xiaomin Sun; Kumpei Tanisawa; Yuping Zhang; Tomoko Ito; Satomi Oshima; Mitsuru Higuchi; Zhen Bo Cao

doi:10.1159/000504873

Effect of Vitamin D Supplementation on Body Composition and Physical Fitness in Healthy Adults: A Double-Blind, Randomized Controlled Trial

Xiaomin Sun, Kumpei Tanisawa, Yuping Zhang, Tomoko Ito, Satomi Oshima, Mitsuru Higuchi, Zhen Bo Cao

School of Sport Sciences

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Introduction: This study aimed to clarify whether 1 year of vitamin D₃ supplementation has a direct effect on body composition and physical fitness in healthy adults. Methods: Ninety-five participants randomly received either 420 IU vitamin D₃ per day (n = 48) or placebo (n = 47) in a double-blind manner for 1 year. Lean body mass and percentage body fat were determined. Physical fitness including hand grip strength, leg extension power and cardiorespiratory fitness (CRF) were assessed. Serum 25-hydroxyvitamin D (25[OH]D) and 1,25-dihydroxyvitamin D (1,25[OH]₂D) concentrations were assessed using ELISA kits. Results: Serum 25(OH)D and (1,25[OH]₂D) concentrations significantly increased by approximately 11.2 ± 9.2 ng/mL (p_interaction <0.001)and 7.0 ± 7.8 pg/mL (p_interaction <0.001) after 1 year of vitamin D₃ supplementation respectively. Lean body mass significantly increased from 43.8 ± 9.6 to 44.3 ± 9.8 kg in vitamin D group, while no change was observed in placebo group (from 42.6 ± 8.9 to 42.4± 8.9 kg) after 1 year intervention. Furthermore, no treatment effects on other indicators of body composition and physical fitness were observed. Conclusions:One year of vitamin D supplementation effectively improves lean body mass, but not muscle strength and CRF in healthy adults.

Original language	English
Pages (from-to)	231-237
Number of pages	7
Journal	Annals of Nutrition and Metabolism
Volume	75
Issue number	4
DOIs	https://doi.org/10.1159/000504873
Publication status	Published - 2020 Jan 1

Keywords

25-Hydroxyvitamin D
Body fat
Cardiorespiratory fitness
Hand grip strength
Lean body mass

ASJC Scopus subject areas

Medicine (miscellaneous)
Nutrition and Dietetics

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10.1159/000504873

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@article{728328bf7ca6440192191b58802f26c8,

title = "Effect of Vitamin D Supplementation on Body Composition and Physical Fitness in Healthy Adults: A Double-Blind, Randomized Controlled Trial",

abstract = "Introduction: This study aimed to clarify whether 1 year of vitamin D3 supplementation has a direct effect on body composition and physical fitness in healthy adults. Methods: Ninety-five participants randomly received either 420 IU vitamin D3 per day (n = 48) or placebo (n = 47) in a double-blind manner for 1 year. Lean body mass and percentage body fat were determined. Physical fitness including hand grip strength, leg extension power and cardiorespiratory fitness (CRF) were assessed. Serum 25-hydroxyvitamin D (25[OH]D) and 1,25-dihydroxyvitamin D (1,25[OH]2D) concentrations were assessed using ELISA kits. Results: Serum 25(OH)D and (1,25[OH]2D) concentrations significantly increased by approximately 11.2 ± 9.2 ng/mL (pinteraction <0.001)and 7.0 ± 7.8 pg/mL (pinteraction <0.001) after 1 year of vitamin D3 supplementation respectively. Lean body mass significantly increased from 43.8 ± 9.6 to 44.3 ± 9.8 kg in vitamin D group, while no change was observed in placebo group (from 42.6 ± 8.9 to 42.4± 8.9 kg) after 1 year intervention. Furthermore, no treatment effects on other indicators of body composition and physical fitness were observed. Conclusions:One year of vitamin D supplementation effectively improves lean body mass, but not muscle strength and CRF in healthy adults.",

keywords = "25-Hydroxyvitamin D, Body fat, Cardiorespiratory fitness, Hand grip strength, Lean body mass",

author = "Xiaomin Sun and Kumpei Tanisawa and Yuping Zhang and Tomoko Ito and Satomi Oshima and Mitsuru Higuchi and Cao, {Zhen Bo}",

note = "Funding Information: This study was supported in part by a grant-in-aid for Scientific Research (C) from the Ministry of Education, Culture, Sports, Science and Technology of Japan (to ZB.C.); grants from the National Natural Science Foundation of China (Nos. 31571226, 81703220); and a grant from the Fundamental Research Funds for the Central Universities (No. xjj2018148); the Science and Technology Commission of Shanghai Municipality (No. 16080503300). Publisher Copyright: {\textcopyright} 2019 S. Karger AG, Basel.",

year = "2020",

month = jan,

day = "1",

doi = "10.1159/000504873",

language = "English",

volume = "75",

pages = "231--237",

journal = "Annals of Nutrition and Metabolism",

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publisher = "S. Karger AG",

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TY - JOUR

T1 - Effect of Vitamin D Supplementation on Body Composition and Physical Fitness in Healthy Adults

T2 - A Double-Blind, Randomized Controlled Trial

AU - Sun, Xiaomin

AU - Tanisawa, Kumpei

AU - Zhang, Yuping

AU - Ito, Tomoko

AU - Oshima, Satomi

AU - Higuchi, Mitsuru

AU - Cao, Zhen Bo

N1 - Funding Information: This study was supported in part by a grant-in-aid for Scientific Research (C) from the Ministry of Education, Culture, Sports, Science and Technology of Japan (to ZB.C.); grants from the National Natural Science Foundation of China (Nos. 31571226, 81703220); and a grant from the Fundamental Research Funds for the Central Universities (No. xjj2018148); the Science and Technology Commission of Shanghai Municipality (No. 16080503300). Publisher Copyright: © 2019 S. Karger AG, Basel.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Introduction: This study aimed to clarify whether 1 year of vitamin D3 supplementation has a direct effect on body composition and physical fitness in healthy adults. Methods: Ninety-five participants randomly received either 420 IU vitamin D3 per day (n = 48) or placebo (n = 47) in a double-blind manner for 1 year. Lean body mass and percentage body fat were determined. Physical fitness including hand grip strength, leg extension power and cardiorespiratory fitness (CRF) were assessed. Serum 25-hydroxyvitamin D (25[OH]D) and 1,25-dihydroxyvitamin D (1,25[OH]2D) concentrations were assessed using ELISA kits. Results: Serum 25(OH)D and (1,25[OH]2D) concentrations significantly increased by approximately 11.2 ± 9.2 ng/mL (pinteraction <0.001)and 7.0 ± 7.8 pg/mL (pinteraction <0.001) after 1 year of vitamin D3 supplementation respectively. Lean body mass significantly increased from 43.8 ± 9.6 to 44.3 ± 9.8 kg in vitamin D group, while no change was observed in placebo group (from 42.6 ± 8.9 to 42.4± 8.9 kg) after 1 year intervention. Furthermore, no treatment effects on other indicators of body composition and physical fitness were observed. Conclusions:One year of vitamin D supplementation effectively improves lean body mass, but not muscle strength and CRF in healthy adults.

AB - Introduction: This study aimed to clarify whether 1 year of vitamin D3 supplementation has a direct effect on body composition and physical fitness in healthy adults. Methods: Ninety-five participants randomly received either 420 IU vitamin D3 per day (n = 48) or placebo (n = 47) in a double-blind manner for 1 year. Lean body mass and percentage body fat were determined. Physical fitness including hand grip strength, leg extension power and cardiorespiratory fitness (CRF) were assessed. Serum 25-hydroxyvitamin D (25[OH]D) and 1,25-dihydroxyvitamin D (1,25[OH]2D) concentrations were assessed using ELISA kits. Results: Serum 25(OH)D and (1,25[OH]2D) concentrations significantly increased by approximately 11.2 ± 9.2 ng/mL (pinteraction <0.001)and 7.0 ± 7.8 pg/mL (pinteraction <0.001) after 1 year of vitamin D3 supplementation respectively. Lean body mass significantly increased from 43.8 ± 9.6 to 44.3 ± 9.8 kg in vitamin D group, while no change was observed in placebo group (from 42.6 ± 8.9 to 42.4± 8.9 kg) after 1 year intervention. Furthermore, no treatment effects on other indicators of body composition and physical fitness were observed. Conclusions:One year of vitamin D supplementation effectively improves lean body mass, but not muscle strength and CRF in healthy adults.

KW - 25-Hydroxyvitamin D

KW - Body fat

KW - Cardiorespiratory fitness

KW - Hand grip strength

KW - Lean body mass

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SN - 0250-6807

VL - 75

SP - 231

EP - 237

JO - Annals of Nutrition and Metabolism

JF - Annals of Nutrition and Metabolism

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ER -

Effect of Vitamin D Supplementation on Body Composition and Physical Fitness in Healthy Adults: A Double-Blind, Randomized Controlled Trial

Abstract

Keywords

ASJC Scopus subject areas

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