Effects of Anoectochilus formosanus on endurance capacity in mice

Mayumi Ikeuchi*, Kohji Yamaguchi, Tomio Nishimura, Kazunaga Yazawa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


The present study was designed to determine the effects of Anoectochilus formosanus extract (AFE) on endurance capacity in mice, Four wk-old male mice were given either a vehicle (distilled water) or AFE (500, 1,000 mg/kg) through stomach intubations for 4 wk. Mice were made to perform swimming exercises with weights attached to their tails corresponding to 10% of their body weight. Endurance capacity was evaluated by swimming time to exhaustion. The group treated with 1,000 mg/kg AFE showed a significant improvement (p<0.05) in endurance performance time. The mice were made to swim for 15 min with loads corresponding to 5% of their body weight. In the 1,000 mg/kg body weight of AFE administration group, blood lactate concentration was significantly lower than in the control group. In the AFE administration group, the plasma non-esterfied fatty acid (NEFA) was significantly increased by swimming exercise. AFE treatment also significantly decreased fat accumulation. Liver and gastrocnemius muscle glycogen after 15 min of swimming remained at significantly higher levels in the mice fed 1,000 mg/kg of AFE as compared to the control group. These results suggest that AFE activated utilization of lipid more than glucose as the energy source for performance.

Original languageEnglish
Pages (from-to)40-44
Number of pages5
JournalJournal of Nutritional Science and Vitaminology
Issue number1
Publication statusPublished - 2005 Feb
Externally publishedYes


  • Anoectohilus formosanus
  • Endurance capacity
  • Lactate

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Food Science


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