Effects of astaxanthin in obese mice fed a high-fat diet

Mayumi Ikeuchi, Tomoyuki Koyama, Jiro Takahashi, Kazunaga Yazawa*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

175 Citations (Scopus)


Astaxanthin is a natural antioxidant carotenoid that occurs in a wide variety of living organisms. We investigated the effects of astaxanthin supplementation in obese mice fed a high-fat diet. Astaxanthin inhibited the increases in body weight and weight of adipose tissue that result from feeding a high-fat diet. In addition, astaxanthin reduced liver weight, liver triglyceride, plasma triglyceride, and total cholesterol. These results suggest that astaxanthin might be of value in reducing the likelihood of obesity and metabolic syndrome in affluent societies.

Original languageEnglish
Pages (from-to)893-899
Number of pages7
JournalBioscience, Biotechnology and Biochemistry
Issue number4
Publication statusPublished - 2007
Externally publishedYes


  • Astaxanthin
  • High-fat diet
  • Obesity

ASJC Scopus subject areas

  • Bioengineering
  • Biotechnology
  • Biochemistry
  • General Biochemistry,Genetics and Molecular Biology
  • Chemistry (miscellaneous)
  • Applied Microbiology and Biotechnology
  • Food Science


Dive into the research topics of 'Effects of astaxanthin in obese mice fed a high-fat diet'. Together they form a unique fingerprint.

Cite this