Effects of Benzylglucosinolate on Endurance Capacity in Mice

Mayumi Ikeuchi; Tomoyuki Koyama; Shin Takei; Takao Kino; Kazunaga Yazawa

doi:10.1248/jhs.55.178

Effects of Benzylglucosinolate on Endurance Capacity in Mice

Mayumi Ikeuchi, Tomoyuki Koyama, Shin Takei, Takao Kino, Kazunaga Yazawa^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

The present study was designed to determine the effects ofbenzylglucosinolate on endurance capacity in mice. Mice were orally administered either vehicle or benzylglucosinolate (0.015 or 0.03 mg/kg) via stomach intubation for a 6-week period. Benzylglucosinolate-treated mice showed a significantly increased endurance exercise ca- pacity. Benzylglucosinolate significantly decreased blood lactate concentrations and significantly elevated plasma non-esterified fatty acid (NEFA) during exercise. Lastly, benzylglucosinolate treatment significantly decreased fat accumulation. These data suggest that benzylglucosinolate enhanced swimming endurance due to increased fatty acid utilization as an energy source.

Original language	English
Pages (from-to)	178-182
Number of pages	5
Journal	Journal of Health Science
Volume	55
Issue number	2
DOIs	https://doi.org/10.1248/jhs.55.178
Publication status	Published - 2009 Apr
Externally published	Yes

Keywords

Benzylglucosinolate
Endurance capacity
Lepidium meyenii (Maca)

ASJC Scopus subject areas

Toxicology
Health, Toxicology and Mutagenesis

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AU - Takei, Shin

AU - Kino, Takao

AU - Yazawa, Kazunaga

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AB - The present study was designed to determine the effects ofbenzylglucosinolate on endurance capacity in mice. Mice were orally administered either vehicle or benzylglucosinolate (0.015 or 0.03 mg/kg) via stomach intubation for a 6-week period. Benzylglucosinolate-treated mice showed a significantly increased endurance exercise ca- pacity. Benzylglucosinolate significantly decreased blood lactate concentrations and significantly elevated plasma non-esterified fatty acid (NEFA) during exercise. Lastly, benzylglucosinolate treatment significantly decreased fat accumulation. These data suggest that benzylglucosinolate enhanced swimming endurance due to increased fatty acid utilization as an energy source.

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Effects of Benzylglucosinolate on Endurance Capacity in Mice

Abstract

Keywords

ASJC Scopus subject areas

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