Effects of implantation on the mechanical properties of the Polyurethane diaphragm of left ventricular assist devices

Kozaburo Hayashi; Takehisa Matsuda; Hisateru Takano; Mitsuo Umezu; Yoshiyuki Taenaka; Takao Nakamura

doi:10.1016/0142-9612(85)90068-7

Effects of implantation on the mechanical properties of the Polyurethane diaphragm of left ventricular assist devices

Kozaburo Hayashi^*, Takehisa Matsuda, Hisateru Takano, Mitsuo Umezu, Yoshiyuki Taenaka, Takao Nakamura

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Tensile properties of blood pump diaphragms made from a segmented polyether polyurethane (Toyobo TM5) were studied after implanting in goats for variable periods of time up to 72 days. The implantation decreased the tensile strength and ultimate elongation at break, while the elastic modulus increased very slightly. These changes in the strength and ductility were primarily caused by the contact of material with blood rather than by the mechanical fatigue of material. Mechanical stability was greatly improved by removing residual oligomers from the material by a refining procedure. The refined polyurethane has characteristics favourable for blood pump applications.

Original language	English
Pages (from-to)	82-88
Number of pages	7
Journal	Biomaterials
Volume	6
Issue number	2
DOIs	https://doi.org/10.1016/0142-9612(85)90068-7
Publication status	Published - 1985 Mar
Externally published	Yes

Keywords

Polymers
Segmented polyether polyurethane
implantation
in vitro fatigue test
left ventricular assist device
tensile properties

ASJC Scopus subject areas

Bioengineering
Ceramics and Composites
Biophysics
Biomaterials
Mechanics of Materials

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10.1016/0142-9612(85)90068-7

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title = "Effects of implantation on the mechanical properties of the Polyurethane diaphragm of left ventricular assist devices",

abstract = "Tensile properties of blood pump diaphragms made from a segmented polyether polyurethane (Toyobo TM5) were studied after implanting in goats for variable periods of time up to 72 days. The implantation decreased the tensile strength and ultimate elongation at break, while the elastic modulus increased very slightly. These changes in the strength and ductility were primarily caused by the contact of material with blood rather than by the mechanical fatigue of material. Mechanical stability was greatly improved by removing residual oligomers from the material by a refining procedure. The refined polyurethane has characteristics favourable for blood pump applications.",

keywords = "Polymers, Segmented polyether polyurethane, implantation, in vitro fatigue test, left ventricular assist device, tensile properties",

author = "Kozaburo Hayashi and Takehisa Matsuda and Hisateru Takano and Mitsuo Umezu and Yoshiyuki Taenaka and Takao Nakamura",

note = "Funding Information: This research work was supported financially in part by: Grant-in-Aid for Scientific Research from the Ministry of Education (No. 557322 and No. 57570520); Research Grant for Cardiovascular Diseases and Grant for Scientific Research Expenses for Health and Welfare Program from the Ministry of Health and Welfare; and Japan Heart Foundation Research Grant for 1981 (ali with Dr Kozaburo Hayashi as the principal investigator). The authors wish to thank Messrs K. Murayama and M. Tanaka of Toyobo Co. and DrT. Tsunetsugu of Sumitomo Bakelite Co. for providing materials used in this study.",

year = "1985",

month = mar,

doi = "10.1016/0142-9612(85)90068-7",

language = "English",

volume = "6",

pages = "82--88",

journal = "Biomaterials",

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AU - Hayashi, Kozaburo

AU - Matsuda, Takehisa

AU - Takano, Hisateru

AU - Umezu, Mitsuo

AU - Taenaka, Yoshiyuki

AU - Nakamura, Takao

N1 - Funding Information: This research work was supported financially in part by: Grant-in-Aid for Scientific Research from the Ministry of Education (No. 557322 and No. 57570520); Research Grant for Cardiovascular Diseases and Grant for Scientific Research Expenses for Health and Welfare Program from the Ministry of Health and Welfare; and Japan Heart Foundation Research Grant for 1981 (ali with Dr Kozaburo Hayashi as the principal investigator). The authors wish to thank Messrs K. Murayama and M. Tanaka of Toyobo Co. and DrT. Tsunetsugu of Sumitomo Bakelite Co. for providing materials used in this study.

PY - 1985/3

Y1 - 1985/3

N2 - Tensile properties of blood pump diaphragms made from a segmented polyether polyurethane (Toyobo TM5) were studied after implanting in goats for variable periods of time up to 72 days. The implantation decreased the tensile strength and ultimate elongation at break, while the elastic modulus increased very slightly. These changes in the strength and ductility were primarily caused by the contact of material with blood rather than by the mechanical fatigue of material. Mechanical stability was greatly improved by removing residual oligomers from the material by a refining procedure. The refined polyurethane has characteristics favourable for blood pump applications.

AB - Tensile properties of blood pump diaphragms made from a segmented polyether polyurethane (Toyobo TM5) were studied after implanting in goats for variable periods of time up to 72 days. The implantation decreased the tensile strength and ultimate elongation at break, while the elastic modulus increased very slightly. These changes in the strength and ductility were primarily caused by the contact of material with blood rather than by the mechanical fatigue of material. Mechanical stability was greatly improved by removing residual oligomers from the material by a refining procedure. The refined polyurethane has characteristics favourable for blood pump applications.

KW - Polymers

KW - Segmented polyether polyurethane

KW - implantation

KW - in vitro fatigue test

KW - left ventricular assist device

KW - tensile properties

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SN - 0142-9612

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EP - 88

JO - Biomaterials

JF - Biomaterials

IS - 2

ER -

Effects of implantation on the mechanical properties of the Polyurethane diaphragm of left ventricular assist devices

Abstract

Keywords

ASJC Scopus subject areas

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