Effects of intrinsic noise in temperature-compensated models for circadian rhythms

Sho Ichikawa; Yohei Ito; Gen Kurosawa; Kenko Uchida

Effects of intrinsic noise in temperature-compensated models for circadian rhythms

Sho Ichikawa^*, Yohei Ito, Gen Kurosawa, Kenko Uchida

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Circadian rhythms, which are observed in most of organisms, e.g. bacteria, fungi, plants, and animals, are self-sustained oscillations with about 24 hours period and a remarkable temperature compensation property. By using the temperature-compensated and robust temperature-compensated deterministic models for circadian rhythms, we perform the stochastic simulations based on the Gillespie's method by changing temperature over a wide range, and discuss how the deterministic temperature compensation properties fluctuate over the range of temperature in the stochastic setting reflecting the intrinsically noisy environments. In order to strengthen the inference from the stochastic simulations, we also execute a qualitative analysis based on the linear noise approximation.

Original language	English
Title of host publication	ICCAS-SICE 2009 - ICROS-SICE International Joint Conference 2009, Proceedings
Pages	200-205
Number of pages	6
Publication status	Published - 2009
Event	ICROS-SICE International Joint Conference 2009, ICCAS-SICE 2009 - Fukuoka Duration: 2009 Aug 18 → 2009 Aug 21

Other

Other	ICROS-SICE International Joint Conference 2009, ICCAS-SICE 2009
City	Fukuoka
Period	09/8/18 → 09/8/21

Keywords

Circadian rhythm
Intrinsic noise
Temperature compensation

ASJC Scopus subject areas

Information Systems
Control and Systems Engineering
Industrial and Manufacturing Engineering

Cite this

@inproceedings{7c83b899c0094f0ea6bfa3d93f22de35,

title = "Effects of intrinsic noise in temperature-compensated models for circadian rhythms",

abstract = "Circadian rhythms, which are observed in most of organisms, e.g. bacteria, fungi, plants, and animals, are self-sustained oscillations with about 24 hours period and a remarkable temperature compensation property. By using the temperature-compensated and robust temperature-compensated deterministic models for circadian rhythms, we perform the stochastic simulations based on the Gillespie's method by changing temperature over a wide range, and discuss how the deterministic temperature compensation properties fluctuate over the range of temperature in the stochastic setting reflecting the intrinsically noisy environments. In order to strengthen the inference from the stochastic simulations, we also execute a qualitative analysis based on the linear noise approximation.",

keywords = "Circadian rhythm, Intrinsic noise, Temperature compensation",

author = "Sho Ichikawa and Yohei Ito and Gen Kurosawa and Kenko Uchida",

year = "2009",

language = "English",

isbn = "9784907764333",

pages = "200--205",

booktitle = "ICCAS-SICE 2009 - ICROS-SICE International Joint Conference 2009, Proceedings",

note = "ICROS-SICE International Joint Conference 2009, ICCAS-SICE 2009 ; Conference date: 18-08-2009 Through 21-08-2009",

}

TY - GEN

T1 - Effects of intrinsic noise in temperature-compensated models for circadian rhythms

AU - Ichikawa, Sho

AU - Ito, Yohei

AU - Kurosawa, Gen

AU - Uchida, Kenko

PY - 2009

Y1 - 2009

N2 - Circadian rhythms, which are observed in most of organisms, e.g. bacteria, fungi, plants, and animals, are self-sustained oscillations with about 24 hours period and a remarkable temperature compensation property. By using the temperature-compensated and robust temperature-compensated deterministic models for circadian rhythms, we perform the stochastic simulations based on the Gillespie's method by changing temperature over a wide range, and discuss how the deterministic temperature compensation properties fluctuate over the range of temperature in the stochastic setting reflecting the intrinsically noisy environments. In order to strengthen the inference from the stochastic simulations, we also execute a qualitative analysis based on the linear noise approximation.

AB - Circadian rhythms, which are observed in most of organisms, e.g. bacteria, fungi, plants, and animals, are self-sustained oscillations with about 24 hours period and a remarkable temperature compensation property. By using the temperature-compensated and robust temperature-compensated deterministic models for circadian rhythms, we perform the stochastic simulations based on the Gillespie's method by changing temperature over a wide range, and discuss how the deterministic temperature compensation properties fluctuate over the range of temperature in the stochastic setting reflecting the intrinsically noisy environments. In order to strengthen the inference from the stochastic simulations, we also execute a qualitative analysis based on the linear noise approximation.

KW - Circadian rhythm

KW - Intrinsic noise

KW - Temperature compensation

UR - http://www.scopus.com/inward/record.url?scp=77951114894&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77951114894&partnerID=8YFLogxK

M3 - Conference contribution

AN - SCOPUS:77951114894

SN - 9784907764333

SP - 200

EP - 205

BT - ICCAS-SICE 2009 - ICROS-SICE International Joint Conference 2009, Proceedings

T2 - ICROS-SICE International Joint Conference 2009, ICCAS-SICE 2009

Y2 - 18 August 2009 through 21 August 2009

ER -

Effects of intrinsic noise in temperature-compensated models for circadian rhythms

Abstract

Other

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this