@article{2bb6808b9b6940b6824d1a078179449c,
title = "Effects of resistance exercise on cerebral redox regulation and cognition: An interplay between muscle and brain",
abstract = "This review highlighted resistance training as an important training type for the brain. Most studies that use physical exercise for the prevention or treatment of neurodegenerative diseases have focused on aerobic physical exercise, revealing different behavioral, biochemical, and molecular effects. However, recent studies have shown that resistance training can also significantly contribute to the prevention of neurodegenerative diseases as well as to the maintenance, development, and recovery of brain activities through specific neurochemical adaptations induced by the training. In this scenario we observed the results of several studies published in different journals in the last 20 years, focusing on the effects of resistance training on three main neurological aspects: Neuroprotective mechanisms, oxidative stress, and cognition. Systematic database searches of PubMed, Web of Science, Scopus, and Medline were performed to identify peer-reviewed studies from the 2000s. Combinations of keywords related to brain disease, aerobic/resistance, or strength physical exercise were used. Other variables were not addressed in this review but should be considered for a complete understanding of the effects of training in the brain.",
keywords = "BDNF, Brain, Cognition, Oxidative stress, Physical exercise, Redox, Resistance training",
author = "Pinho, {Ricardo A.} and Aguiar, {Aderbal S.} and Zsolt Rad{\'a}k",
note = "Funding Information: This study was supported by OTKA (112810) and National Excellence Program (126823), and Scientific Excellence Program TUDFO/51757/2019-ITM, at the University of Physical Education, Innovation and Technology Ministry, Hungary, grants awarded to Z.R., National Council of Technological and Scientific Development-CNPq/Brazil, and Coordination for the Improvement of Higher Education Personnel-CAPES/Brazil. We also thank Rafael Barreto Pinho for the final artwork of figures. Funding Information: Authors{\textquoteright} contributions: R.A.P., A.A.S., and Z.R. contributed by searching and all contributed to the manuscript writing. All authors have read and approved the final version of the manuscript, and agree with the order of writing. All authors have read and approved the final version of the manuscript, and agree with the order of presentation of the authors. Acknowledgments: This study was supported by OTKA (112810) and National Excellence Program (126823), AancdknSocwienletdifgicmEexnctesl:leTnhcies Psrtougdrya mwaTsU sDupFpOo/5rt1e7d5 7b/y20O19T-KITAM (,1a1t2t8h1e0)U annidve NrsaittyioonfaPl hEyxscieclalelnEcdeu Pcraotigorna,mIn (n1o2v6a8t2i3o)n, and Scientific Excellence Program TUDFO/51757/2019-ITM, at the University of Physical Education, Innovation Development-CNPq/Brazil, and Coordination for the Improvement of Higher Education Personnel-CAPES/Brazil. and Technology Ministry, Hungary, grants awarded to Z.R., National Council of Technological and Scientific We also thank Rafael Barreto Pinho for the final artwork of figures. Development-CNPq/Brazil, and Coordination for the Improvement of Higher Education Personnel-CAPES/Brazil. We also thank Rafael Barreto Pinho for the final artwork of figures. Publisher Copyright: {\textcopyright} 2019, MDPI AG. All rights reserved.",
year = "2019",
month = nov,
doi = "10.3390/antiox8110529",
language = "English",
volume = "8",
journal = "Antioxidants",
issn = "2076-3921",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "11",
}