Enantioselective total synthesis of (-)-erinacine B

Hideaki Watanabe, Masashi Takano, Akinori Umino, Toshiya Ito, Hiroyuki Ishikawa, Masahisa Nakada*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Citations (Scopus)


(Chemical Equation Presented) The first enantioselective total synthesis of (-)-erinacine B has been achieved. Our approach features convergent construction of the 5-6-7 tricyclic cyathane core system via chiral building blocks prepared using asymmetric catalysis developed by us and highly stereoselective construction of all stereogenic centers in the aglycon.

Original languageEnglish
Pages (from-to)359-362
Number of pages4
JournalOrganic Letters
Issue number2
Publication statusPublished - 2007 Jan 18

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


Dive into the research topics of 'Enantioselective total synthesis of (-)-erinacine B'. Together they form a unique fingerprint.

Cite this