Endocrine and immune responses to resistance training in prostate cancer patients

D. A. Galvão; K. Nosaka; D. R. Taaffe; J. Peake; N. Spry; K. Suzuki; K. Yamaya; M. R. McGuigan; L. J. Kristjanson; R. U. Newton

doi:10.1038/sj.pcan.4500991

Endocrine and immune responses to resistance training in prostate cancer patients

D. A. Galvão^*, K. Nosaka, D. R. Taaffe, J. Peake, N. Spry, K. Suzuki, K. Yamaya, M. R. McGuigan, L. J. Kristjanson, R. U. Newton

^*Corresponding author for this work

School of Sport Sciences

Research output: Contribution to journal › Article › peer-review

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Abstract

This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-α and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.

Original language	English
Pages (from-to)	160-165
Number of pages	6
Journal	Prostate Cancer and Prostatic Diseases
Volume	11
Issue number	2
DOIs	https://doi.org/10.1038/sj.pcan.4500991
Publication status	Published - 2008 Jun

ASJC Scopus subject areas

Oncology
Urology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Endocrine and immune responses to resistance training in prostate cancer patients",

abstract = "This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-α and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.",

author = "Galv{\~a}o, {D. A.} and K. Nosaka and Taaffe, {D. R.} and J. Peake and N. Spry and K. Suzuki and K. Yamaya and McGuigan, {M. R.} and Kristjanson, {L. J.} and Newton, {R. U.}",

note = "Funding Information: This study was partly supported by a grant-in-aid for SCOE Research and Young Scientist (A) from the Ministry of Education, Culture, Sports, Science and Technology in Japan (grant no. 17680047), Life Fitness Academy Michael Pollock Memorial Grant and Fitness Technology.",

year = "2008",

month = jun,

doi = "10.1038/sj.pcan.4500991",

language = "English",

volume = "11",

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journal = "Prostate Cancer and Prostatic Diseases",

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AU - Galvão, D. A.

AU - Nosaka, K.

AU - Taaffe, D. R.

AU - Peake, J.

AU - Spry, N.

AU - Suzuki, K.

AU - Yamaya, K.

AU - McGuigan, M. R.

AU - Kristjanson, L. J.

AU - Newton, R. U.

N1 - Funding Information: This study was partly supported by a grant-in-aid for SCOE Research and Young Scientist (A) from the Ministry of Education, Culture, Sports, Science and Technology in Japan (grant no. 17680047), Life Fitness Academy Michael Pollock Memorial Grant and Fitness Technology.

PY - 2008/6

Y1 - 2008/6

N2 - This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-α and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.

AB - This study examined the effect of 20 weeks resistance training on a range of serum hormones and inflammatory markers at rest, and following acute bouts of exercise in prostate cancer patients undergoing androgen deprivation. Ten patients exercised twice weekly at high intensity for several upper and lower-body muscle groups. Neither testosterone nor prostate-specific antigen changed at rest or following an acute bout of exercise. However, serum growth hormone (GH), dehydroepiandrosterone (DHEA), interleukin-6, tumor necrosis factor-α and differential blood leukocyte counts increased (P < 0.05) following acute exercise. Resistance exercise does not appear to compromise testosterone suppression, and acute elevations in serum GH and DHEA may partly underlie improvements observed in physical function.

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JO - Prostate Cancer and Prostatic Diseases

JF - Prostate Cancer and Prostatic Diseases

IS - 2

ER -

Endocrine and immune responses to resistance training in prostate cancer patients

Abstract

ASJC Scopus subject areas

UN SDGs

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