Takashi Kato*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Erythropoietin is the primary and physiological regulator of erythropoiesis, that is, the production of red blood cells. It is a glycoprotein produced predominantly in the fetal liver and the adult kidney. It circulates into the adult bone marrow, and binds to its dimerizing receptor on the surface of erythroid progenitor cells to promote cell survival, proliferation, and differentiation. Other nonhematopoietic roles of neuroprotection, cardioprotection, renoprotection, and wound healing have been reported.

Original languageEnglish
Title of host publicationHandbook of Hormones
Subtitle of host publicationComparative Endocrinology for Basic and Clinical Research
Number of pages4
ISBN (Electronic)9780128206492
Publication statusPublished - 2021 Jan 1


  • Cytokine
  • Erythrocytes
  • Erythroids
  • Erythropoiesis
  • Hematopoiesis
  • Hematopoietic growth factor
  • Red blood cells

ASJC Scopus subject areas

  • Medicine(all)


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