Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption

Ayano Kitamura; Marina Komatsu; Yoshimichi Ohki; Maya Mizuno; Miki Hirabayashi; Hiroaki Kojima

doi:10.1109/CEIDP.2015.7351989

Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption

Ayano Kitamura, Marina Komatsu, Yoshimichi Ohki, Maya Mizuno, Miki Hirabayashi, Hiroaki Kojima

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Citations (Scopus)

Abstract

A new research trend that regards deoxyribonucleic acid (DNA) as a new dielectric polymeric material has been emerging in recent years. Especially for such application purposes, a simple easy-to-use method for determining the higher-order structure of synthetic DNA is desirable. From this viewpoint, we demonstrated in this research that far-infrared absorption spectroscopy can be a tool to determine the DNA higher-order structure and we calculated experimentally the integrated molar absorption coefficients per nucleotide with thymine at various frequencies. Therefore, using these coefficients, the number of thymine base on a single stranded DNA can be estimated by far-infrared spectroscopy.

Original language	English
Title of host publication	Annual Report - Conference on Electrical Insulation and Dielectric Phenomena, CEIDP
Publisher	Institute of Electrical and Electronics Engineers Inc.
Pages	617-620
Number of pages	4
Volume	2015-December
ISBN (Print)	9781467374972
DOIs	https://doi.org/10.1109/CEIDP.2015.7351989
Publication status	Published - 2015 Dec 9
Event	IEEE Conference on Electrical Insulation and Dielectric Phenomena, CEIDP 2015 - Ann Arbor, United States Duration: 2015 Oct 18 → 2015 Oct 21

Other

Other	IEEE Conference on Electrical Insulation and Dielectric Phenomena, CEIDP 2015
Country/Territory	United States
City	Ann Arbor
Period	15/10/18 → 15/10/21

Keywords

deoxyribonucleic acid
integrated molar absorbance coefficient
nucleotide
terahertz wave
thymine

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Electrical and Electronic Engineering

Access to Document

10.1109/CEIDP.2015.7351989

Cite this

Kitamura, A., Komatsu, M., Ohki, Y., Mizuno, M., Hirabayashi, M., & Kojima, H. (2015). Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption. In Annual Report - Conference on Electrical Insulation and Dielectric Phenomena, CEIDP (Vol. 2015-December, pp. 617-620). Article 7351989 Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CEIDP.2015.7351989

Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption. / Kitamura, Ayano; Komatsu, Marina; Ohki, Yoshimichi et al.
Annual Report - Conference on Electrical Insulation and Dielectric Phenomena, CEIDP. Vol. 2015-December Institute of Electrical and Electronics Engineers Inc., 2015. p. 617-620 7351989.

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Kitamura, A, Komatsu, M, Ohki, Y, Mizuno, M, Hirabayashi, M & Kojima, H 2015, Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption. in Annual Report - Conference on Electrical Insulation and Dielectric Phenomena, CEIDP. vol. 2015-December, 7351989, Institute of Electrical and Electronics Engineers Inc., pp. 617-620, IEEE Conference on Electrical Insulation and Dielectric Phenomena, CEIDP 2015, Ann Arbor, United States, 15/10/18. https://doi.org/10.1109/CEIDP.2015.7351989

Kitamura A, Komatsu M, Ohki Y, Mizuno M, Hirabayashi M, Kojima H. Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption. In Annual Report - Conference on Electrical Insulation and Dielectric Phenomena, CEIDP. Vol. 2015-December. Institute of Electrical and Electronics Engineers Inc. 2015. p. 617-620. 7351989 doi: 10.1109/CEIDP.2015.7351989

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title = "Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption",

abstract = "A new research trend that regards deoxyribonucleic acid (DNA) as a new dielectric polymeric material has been emerging in recent years. Especially for such application purposes, a simple easy-to-use method for determining the higher-order structure of synthetic DNA is desirable. From this viewpoint, we demonstrated in this research that far-infrared absorption spectroscopy can be a tool to determine the DNA higher-order structure and we calculated experimentally the integrated molar absorption coefficients per nucleotide with thymine at various frequencies. Therefore, using these coefficients, the number of thymine base on a single stranded DNA can be estimated by far-infrared spectroscopy.",

keywords = "deoxyribonucleic acid, integrated molar absorbance coefficient, nucleotide, terahertz wave, thymine",

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AU - Hirabayashi, Miki

AU - Kojima, Hiroaki

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N2 - A new research trend that regards deoxyribonucleic acid (DNA) as a new dielectric polymeric material has been emerging in recent years. Especially for such application purposes, a simple easy-to-use method for determining the higher-order structure of synthetic DNA is desirable. From this viewpoint, we demonstrated in this research that far-infrared absorption spectroscopy can be a tool to determine the DNA higher-order structure and we calculated experimentally the integrated molar absorption coefficients per nucleotide with thymine at various frequencies. Therefore, using these coefficients, the number of thymine base on a single stranded DNA can be estimated by far-infrared spectroscopy.

AB - A new research trend that regards deoxyribonucleic acid (DNA) as a new dielectric polymeric material has been emerging in recent years. Especially for such application purposes, a simple easy-to-use method for determining the higher-order structure of synthetic DNA is desirable. From this viewpoint, we demonstrated in this research that far-infrared absorption spectroscopy can be a tool to determine the DNA higher-order structure and we calculated experimentally the integrated molar absorption coefficients per nucleotide with thymine at various frequencies. Therefore, using these coefficients, the number of thymine base on a single stranded DNA can be estimated by far-infrared spectroscopy.

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Estimation of the number of nucleotides with thymine in deoxyribonucleic acid by far-infrared absorption

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