TY - GEN
T1 - Evaluation of the performance limit of MPPC for ToF-PET
AU - Tsujikawa, Takayuki
AU - Kataoka, Jun
AU - Ambe, Takahiro
AU - Fujita, Takuya
AU - Kurei, Yota
AU - Sato, Goro
AU - Ikeda, Hirolazu
PY - 2016/3/10
Y1 - 2016/3/10
N2 - In recent years, multi-pixel photon counters (MPPCs) have been actively studied for use in a module for such next-generation PET systems as MRI-PET, DoI-PET, and ToF-PET scanners. In particular, Time of Flight (ToF) measurement is a challenging approach to identify the position of a γ-ray source, according to differences in the arrival times of annihilation γ rays after positron decay. Several simulations suggest a substantial improvement in the signal-to-noise ratio of PET images when using ToF information. However, ToF-PET performance is determined by the time resolution of a γ-ray sensor (including scintillators, photo-sensors and readout electronics) as a whole, thus making it often difficult to achieve ToF resolution as good as 500 ps (FWHM) in actual PET systems. This paper describes our development of a new method of ToF measurement using MPPC-based scintillation detectors. We showed that our method effectively reduces the contamination of dark noise, and minimizes the effects of time walk and timing jitter. The best ToF resolution of 213 ps (FWHM) was achieved by coupling 3×3×10 mm3 Ce:LYSO crystal with a 3×3 mm2 pixel detector. We conclude by commenting on our ultra-fast ASIC for 16-ch MPPC readout as pertaining to future applications in MPPC-PET scanners with ToF measurement capability.
AB - In recent years, multi-pixel photon counters (MPPCs) have been actively studied for use in a module for such next-generation PET systems as MRI-PET, DoI-PET, and ToF-PET scanners. In particular, Time of Flight (ToF) measurement is a challenging approach to identify the position of a γ-ray source, according to differences in the arrival times of annihilation γ rays after positron decay. Several simulations suggest a substantial improvement in the signal-to-noise ratio of PET images when using ToF information. However, ToF-PET performance is determined by the time resolution of a γ-ray sensor (including scintillators, photo-sensors and readout electronics) as a whole, thus making it often difficult to achieve ToF resolution as good as 500 ps (FWHM) in actual PET systems. This paper describes our development of a new method of ToF measurement using MPPC-based scintillation detectors. We showed that our method effectively reduces the contamination of dark noise, and minimizes the effects of time walk and timing jitter. The best ToF resolution of 213 ps (FWHM) was achieved by coupling 3×3×10 mm3 Ce:LYSO crystal with a 3×3 mm2 pixel detector. We conclude by commenting on our ultra-fast ASIC for 16-ch MPPC readout as pertaining to future applications in MPPC-PET scanners with ToF measurement capability.
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U2 - 10.1109/NSSMIC.2014.7430884
DO - 10.1109/NSSMIC.2014.7430884
M3 - Conference contribution
AN - SCOPUS:84965064409
T3 - 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
BT - 2014 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2014
Y2 - 8 November 2014 through 15 November 2014
ER -