TY - JOUR
T1 - Ex vivo evaluation of high-intensity focused ultrasound with ultrasonic-induced cavitation bubbles
AU - Abe, Nobutaka
AU - Nakamoto, Hidekazu
AU - Suzuki, Takashi
AU - Muragaki, Yoshihiro
AU - Iseki, Hiroshi
N1 - Funding Information:
transducer. This research was partially supported by the Ministry of Economy, Trade and Industry, Japan (METI, Standardization Promotion Project). A part of this research was supported by a grant from the Japan Society for the Promotion of Science (JSPS) through the ‘‘Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST Program),’’ initiated by the Council for Science and Technology Policy (CSTP).
PY - 2014/1
Y1 - 2014/1
N2 - Purpose: In high-intensity focused ultrasound (HIFU) comprising high-intensity burst ultrasound (triggering pulse) and medium-intensity continuous wave ultrasound (heating wave), optimizing the effects of the triggering pulse conditions on the coagulated volume may help to reduce treatment times. Methods: HIFU combined with a triggering pulse was applied to chicken deep pectoral muscles. The acoustic power of the heating wave was set to 36, 54, or 72 W. Four different triggering pulse conditions were used: heating wave only; or pulse widths and pulse repetition frequencies of 30 μs and 1 kHz, 300 μs, and 100 Hz, or 3 ms and 10 Hz. Results: Compared to the heating wave only condition, the coagulated volume was significantly larger under all conditions that included a triggering pulse. Significant differences were also observed in the ellipticity of the coagulated region between some conditions. Conclusion: HIFU combined with a triggering pulse may play an important role in reducing treatment times.
AB - Purpose: In high-intensity focused ultrasound (HIFU) comprising high-intensity burst ultrasound (triggering pulse) and medium-intensity continuous wave ultrasound (heating wave), optimizing the effects of the triggering pulse conditions on the coagulated volume may help to reduce treatment times. Methods: HIFU combined with a triggering pulse was applied to chicken deep pectoral muscles. The acoustic power of the heating wave was set to 36, 54, or 72 W. Four different triggering pulse conditions were used: heating wave only; or pulse widths and pulse repetition frequencies of 30 μs and 1 kHz, 300 μs, and 100 Hz, or 3 ms and 10 Hz. Results: Compared to the heating wave only condition, the coagulated volume was significantly larger under all conditions that included a triggering pulse. Significant differences were also observed in the ellipticity of the coagulated region between some conditions. Conclusion: HIFU combined with a triggering pulse may play an important role in reducing treatment times.
KW - Cavitation bubbles
KW - High-intensity focused ultrasound (HIFU)
KW - High-intensity therapeutic ultrasound (HITU)
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U2 - 10.1007/s10396-013-0469-9
DO - 10.1007/s10396-013-0469-9
M3 - Article
AN - SCOPUS:84893677152
SN - 1344-1388
VL - 41
SP - 3
EP - 9
JO - Japanese Journal of Medical Ultrasonics
JF - Japanese Journal of Medical Ultrasonics
IS - 1
ER -