Abstract
Physical inactivity is a major contributor to the development of lifestyle-related diseases, including cardiovascular diseases (Lee et al. 2013; Oppewal et al. 2013), certain tumors, type 2 diabetes (Kasuga et al. 2013), osteoporosis (Janssen 2012), and even neurodegenerative diseases (Radak et al. 2010; Janssen 2012). This could be partly because the development of the genome at the genesis of humans was associated with a physically active lifestyle. It has been suggested that Stone Age man used 4000 kcal for physical activity on a daily basis (Radak et al. 2013c). Adaptive changes on the DNA sequence are very slow. Therefore, it is not surprising that physical inactivity is a risk factor for a wide range of diseases.
| Original language | English |
|---|---|
| Title of host publication | Hormesis in Health and Disease |
| Publisher | CRC Press |
| Pages | 37-44 |
| Number of pages | 8 |
| ISBN (Electronic) | 9781482205466 |
| ISBN (Print) | 9781482205459 |
| DOIs | |
| Publication status | Published - 2014 Jan 1 |
| Externally published | Yes |
ASJC Scopus subject areas
- Medicine(all)
- Pharmacology, Toxicology and Pharmaceutics(all)
- Biochemistry, Genetics and Molecular Biology(all)
