TY - JOUR
T1 - Facial skin blood flow responses to irritant stimuli in the oral cavity
AU - Kashima, Hideaki
AU - Hayashi, Naoyuki
N1 - Funding Information:
This study was supported by a grant from the Uehara Memorial Foundation and Grant-in-Aid for Challenge Exploratory Research (no. 24650352 ) (to N.H.).
PY - 2013/3
Y1 - 2013/3
N2 - To investigate whether capsaicin and menthol stimuli elicit characteristic responses in facial skin blood flow (SkBF), we observed the facial SkBF response to low and high concentrations of capsaicin and menthol stimuli of 1-ml solution applied to the oral cavity for 20. s in 17 healthy subjects. High concentration of capsaicin significantly increased the SkBF in all of the facial areas monitored. High concentration of menthol stimulus significantly decreased SkBF in the nose and increased that in the eyelid, and upper and lower lips. These results demonstrated that capsaicin and menthol stimuli in the oral cavity elicit characteristic responses in facial SkBF.
AB - To investigate whether capsaicin and menthol stimuli elicit characteristic responses in facial skin blood flow (SkBF), we observed the facial SkBF response to low and high concentrations of capsaicin and menthol stimuli of 1-ml solution applied to the oral cavity for 20. s in 17 healthy subjects. High concentration of capsaicin significantly increased the SkBF in all of the facial areas monitored. High concentration of menthol stimulus significantly decreased SkBF in the nose and increased that in the eyelid, and upper and lower lips. These results demonstrated that capsaicin and menthol stimuli in the oral cavity elicit characteristic responses in facial SkBF.
KW - Capsaicin
KW - Facial skin blood flow
KW - Menthol
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U2 - 10.1016/j.autneu.2012.11.010
DO - 10.1016/j.autneu.2012.11.010
M3 - Article
C2 - 23265982
AN - SCOPUS:84875263482
SN - 1566-0702
VL - 174
SP - 61
EP - 65
JO - Autonomic Neuroscience: Basic and Clinical
JF - Autonomic Neuroscience: Basic and Clinical
IS - 1-2
ER -